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Research Associate

The University of Manchester - Cell Matrix Biology and Regenerative Medicine

Location: Manchester
Salary: £32,236 to £39,609 per annum (according to relevant experience)
Hours: Full Time
Contract Type: Fixed-Term/Contract
Placed On: 22nd August 2019
Closes: 23rd September 2019
Job Ref: BM&H-14465
 

Job Reference : BM&H-14465
Location : Oxford Road, Manchester
Closing Date (DD-MM-YYYY) : 23/09/2019
Salary : £32,236 to £39,609 per annum (according to relevant experience)
Employment Type : Fixed Term
Faculty / Organisational Unit : Biology, Medicine & Health
Division : Cell Matrix Biology and Regenerative Medicine
Hours Per week : Full Time
Contract Duration : Until 20 January 2021

Fibrosis is a major contributor to multiple serious disorders including heart failure, atrial fibrillation, atherosclerosis, hypertension, cancer, lung, liver and kidney failure. A major bottleneck has been our limited understanding of physiological tissue homeostasis that maintains the organization and stiffness of healthy tissues. Without understanding the normal mechanisms, data on the transition to fibrosis are difficult to interpret.

The goal of this project is to elucidate the pathways by which cells sense the properties of their extracellular matrix and adjust rates of matrix synthesis, assembly and degradation to keep those properties constant, and how these mechanisms are overcome in fibrosis. The successful candidate will work with Professor Martin Schwartz to elucidate how cellular stiffness sensing pathways regulate matrix synthesis and turnover. These studies will utilize a combination of biophysical, cell biological and tissue engineering approaches to address these questions.

The ideal candidate has obtained a PhD (or equivalent) degree in genetics, cell biology, molecular biology, cancer biology or related discipline with experience related to the above areas. You will be based in the lab of Martin Schwartz in the vibrant interdisciplinary environment of the Wellcome Trust Centre for Cell-Matrix Research (www.wellcome-matrix.org/) at the University of Manchester.

The School is strongly committed to promoting equality and diversity, including the Athena SWAN charter for gender equality in higher education. The School holds a Silver Award which recognises their good practice in relation to gender; including flexible working arrangements, family-friendly policies, and support to allow staff achieve a good work-life balance. We particularly welcome applications from women for this post. All appointment will be made on merit. For further information, please visit:
https://www.bmh.manchester.ac.uk/about/equality/

Please note that we are unable to respond to enquiries, accept CVs or applications from Recruitment Agencies

Enquiries about vacancy shortlisting and interviews:
Name: Martin Schwartz
Email: martin.schwartz@manchester.ac.uk
General enquiries:
Email: hrservices@manchester.ac.uk
Tel: 0161 275 4499
Technical support:
Email: universityofmanchester@helpmeapply.co.uk
Tel: 0161 850 2004

This vacancy will close for applications at midnight on the closing date.

   
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