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Research Associate (Fixed Term) - Edgar Lab

University of Cambridge - Department of Pathology

Location: Cambridge
Salary: £32,236 to £39,609
Hours: Full Time
Contract Type: Fixed-Term/Contract
Placed On: 9th September 2019
Closes: 24th October 2019
Job Ref: PK20599

We are looking to appoint a post-doctoral research associate to join Dr James Edgar's group, based in the Department of Pathology, University of Cambridge ( The successful candidate will work on a project exploring the role of tethered exosomes in antigen presentation and will explore the fundamental cell biology that governs exosome fusion and fate.

This is a three year position funded by the Wellcome Trust/Royal Society through a Sir Henry Dale fellowship awarded to Dr Edgar.

Candidates must have a PhD in cell biology, immunology or a closely related subject. Experience in membrane trafficking is highly desirable and experience with cell culture, molecular biology, flow cytometry and imaging techniques would be advantageous. Previous experience with electron microscopy is also desirable, although not expected.

Dr James Edgar's research group is interested in the role of exosomes, and particularly tethered exosomes in health and disease. James discovered that exosomes may be retained to the surface of cells by the anti-viral protein tetherin (Edgar et al., eLife, 2016), although the roles tethered exosomes play remains ambiguous. Research in the lab focuses on understanding exosome tethering, advancing our fundamental knowledge of exosome formation, and deciphering which molecules and machineries are involved in exosome fusion with recipient cells.

An ability to work independently and as part of a group is expected. The successful candidate should possess excellent communication and critical thinking skills and will be expected to conduct research to a high standard suitable for presentation and publication. The post holder may also be required to assist in the supervision of students and deliver seminars relating to their research.

(Tetherin is an exosomal tether. Edgar JR et al, eLife, 2016.)

Fixed-term: The funds for this post are available for 3 years in the first instance.

Once an offer of employment has been accepted, the successful candidate will be required to undergo a health assessment.

Applications are welcome from internal candidates who would like to apply for the role on the basis of a secondment from their current role in the University.

To apply online for this vacancy and to view further information about the role, please visit:

General enquiries regarding this position should be directed to  or 01223 333940.

Please quote reference PK20599 on your application and in any correspondence about this vacancy.

The University actively supports equality, diversity and inclusion and encourages applications from all sections of society.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

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