|Salary:||£33,797 to £38,017 per annum|
|Placed On:||20th September 2019|
|Closes:||20th October 2019|
Work Hours: 35.0 Hours per Week
Job Type: Research and Teaching
Division / School: School of Biochemistry
We are looking for a self-motivated and talented scientist to study the role of altered microRNA activity on dendritic spine morphology and synaptic function in mouse models for Alzheimer’s disease. The project will build on our recent discovery that Argonaute 2 (Ago2) phosphorylation regulates the local translation of specific mRNAs and is required for structural and functional plasticity (Rajgor et al., EMBO Journal 2018).
The work will be based initially in the laboratory of Jon Brown in Exeter for in vivo molecular interventions (adenovirus and antagomir injections) and ex vivo slice electrophysiology. This will be followed by biochemical and cell imaging techniques in Jonathan Hanley’s lab in Bristol.
Applicants must have a relevant postgraduate research degree or equivalent professional qualification/experience or be working towards one, with relevant lab experience, and at least one article published in a quality peer-reviewed journal.
We welcome applications from all members of our community and are particularly encouraging those from diverse groups, such as members of the LGBT+ and BAME communities, to join us.
The University of Bristol is committed to equality and we value the diversity of our staff and students.
Type / Role: