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Postdoctoral Research Scientist

The Beatson Institute for Cancer Research

Location: Glasgow
Salary: £31,604 to £41,929
Hours: Full Time
Contract Type: Fixed-Term/Contract
Placed On: 14th February 2020
Closes: 9th April 2020

Professor Owen Sansom

Starting Salary from £31,604 to £41,929 (Depending on experience) plus relocation allowance where appropriate. Initial 3 year fixed term contract. 

Would you like to develop your scientific career in a research institute that is founded on the quality of its people, acknowledged for its collaborative environment and designed to promote the development of the most outstanding and dedicated scientists.  Many early career researchers have already made that decision and at present over 100 of them are now benefiting from our excellent training programme.  

The Cancer Research UK Beatson Institute supports cutting edge research into the molecular mechanisms of cancer development and is one of the leading research institutes in Europe. The Institute provides an outstanding research environment, underpinned by state-of-the-art core services and advanced technologies, with special emphasis on imaging, metabolomics, and in vivo models. 

Our innovative and ambitious research themes focus on understanding the regulation of the tumour microenvironment and cancer metabolism, in particular: 

  • Intrinsic cancer cell vulnerabilities caused by cell growth
  • Interplay between the tumour microenvironment, metastasis and recurrence
  • Biology of early disease, aimed at developing a ‘Precision Prevention’ approach

The Sansom laboratory has a world-leading track record in the development of genetically engineered murine models of colorectal cancer and orthotopic transplantation techniques, which we have used to generate models which represent the major molecular subtypes of colorectal cancer found clinically (Jackstadt et al, Cancer Cell 2019).  We currently have a vacancy for a Postdoctoral Research Scientist who, alongside these cutting-edge models, will use advanced organoid cultures derived from colorectal cancer, to investigate the key processes underlying primary tumour initiation and growth and ultimately metastatic dissemination in a complex tumour in vivo.

The initial focus of your research will be how the epithelial determinants can shape the stroma and drive metastasis. Moreover, you will examine the functional role of the cancer stem cell population and EMT markers in both primary and secondary disease.  These studies will drive the identification and validation of novel therapeutic targets for colorectal cancer, with the ultimate aim of benefitting patients in the clinic.

Applicants must have a PhD in a relevant field, be driven by scientific curiosity and have an excellent publication record in cancer biology. Experience in cancer stem cell biology, molecular biology and/or transcriptional profiling will be an advantage.

To find out more about this unique opportunity to establish advanced skills and expertise in the exciting field of colorectal cancer biology, please contact Andrew Campbell ( for more details.

At the Cancer Research UK Beatson Institute, we are committed to increasing the number of female scientists at this level and strongly encourage female applicants to apply. We have recently introduced a highly attractive, innovative maternity policy, which includes providing a postdoc with support and funding so that their projects can continue during their maternity leave. 

All applications must be made via our website at

Closing date for applications: 09 April 2020

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