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PhD Studentship in Mass Spectrometry: Novel Applications of Liquid MALDI MS for the Analysis of Large Biomolecules

University of Reading - Department of Chemistry / School of Chemistry, Food and Pharmacy

Qualification Type: PhD
Location: Reading
Funding for: UK Students, EU Students
Funding amount: Not Specified
Hours: Full Time
Placed On: 26th February 2020
Closes: 1st May 2020
Reference: GS20-012

Supervisors:  Prof Rainer Cramer, Dr Geoffrey Brown, Prof Michael Morris

Project Overview:  This PhD project will investigate novel applications of liquid MALDI MS in the areas of hydrogen/deuterium exchange for structural biology, native mass spectrometry, top-down biomolecule analyses and enzyme assay and kinetics measurements. In addition, further optimisation of the liquid MADLI ion source and its off-line coupling to other preparative techniques will be investigated with the objective to find the ultimate speed for entire workflows as needed in omics analyses or (bio)assaying. The project is partly funded by our industrial collaborator Waters Corporation.


  • Applicants should hold or expect to gain a minimum of a 2:1 Bachelor Degree or equivalent in the Physical or Life Sciences.
  • Due to restrictions on the funding this studentship is open to UK/EU students.

Funding Details:   

  • Starts September 2020
  • 3-year award
  • Tuition fees plus stipend

How to apply:   

To apply for this studentship please submit an application for a PhD in Chemistry at

*Important note*

  • 1) Please quote the reference ‘GS20-012’ in the ‘Scholarships applied for’ box which appears within the Funding Section of your on-line application.
  • 2) When you are prompted to upload a research proposal, please omit this step.

Application Deadline:  1st May 2020

Further Enquiries:  

Please note that, where a candidate is successful in being awarded funding, this will be confirmed via a formal studentship award letter; this will be provided separately from any Offer of Admission and will be subject to standard checks for eligibility and other criteria. 

For further details please contact Isaac Wilks (

For further project-specific details please contact Prof R. Cramer, Chemistry, University of Reading.

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