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Research Technician

UCL Institute of Neurology - UCL Queen Square Institute of Neurology

Location: London
Salary: £29,089 per annum
Hours: Full Time, Part Time
Contract Type: Fixed-Term/Contract
Placed On: 25th March 2020
Closes: 25th April 2020
Job Ref: 1864546

Applications are invited for a full-time or part-time (0.6 FTE) Research Technician in the Department of Neuromuscular Diseases, UCL Queen Square Institute of Neurology, under the supervision of Professor Henry Houlden.

The successful candidate will provide technical support within a team of researchers based in Prof Houlden’s lab as part of initiatives such as the Michael J Fox Foundation (MJFF) Parkinson’s disease project, the SynaptopathiesNeurogenetics project and The MRC International Centre for Neuromuscular Diseases, UCL Queen Square Institute of Neurology. These are important international projects working with lower and middle income countries on the genetic analysis of neurological disorders and the building of cohorts form clinical trials. Cutting edge genetic techniques will be used such as genome/exome and long-read nanopore and PacBio sequencing. Primarily blood/DNA, clinical details and investigations will be collected on >20,000 samples, the largest of its kind in the world. We will also generate patient fibroblast cells, carry out functional investigations and using these to generate high impact translational results. In addition, the technician will be responsible for culturing and maintaining a range of cell models and analysing cell lines. The appointee will also be trained and carry out molecular biology techniques such as Sanger and next generation array and exome/genome sequencing, be responsible for initial data review and processing and working with the bioinformatic team for analysis. The post will also involve writing talks and working on publications with the team and suit a motivated, ambitious, hardworking person. The post holder will also work closely with academics and clinicians and there will be the opportunity to study for a higher degree such as a PhD part-time during this appointment.

The successful candidate should have a degree (minimum 2:2) in Biological Sciences or a related discipline and a background in molecular biology or cell culture techniques. Experience of working with samples such as Human blood and DNA, excellent time management, and ability to work to strict objectives is essential. Good inter-personal skills with an aptitude to work co-operatively in a multidisciplinary setting, ability to work in a high-pressure environment are also required. Experience of culturing fibroblasts / tissue culture techniques and technical excellence and experimental reproducibility is desirable.

The post is available immediately and is funded from the Michael J Fox Foundation for 16 months full-time or until 30 June 2022 at 0.6 FTE in the first instance. Starting salary on UCL Grade 6, £29,089 per annum (pro-rata for 0.6 FTE) including London Allowance.

You should apply for this post through UCL's online recruitment – where you can download a job description and person specification using ref: 1864546.   

For further information regarding the application process please contact Oksana Shapoval, HR Officer, Queen Square Institute of Neurology, Queen Square, London, WC1N 3BG (email:

Please contact Prof Henry Houlden for more information about the role (

Closing Date: 25 April 2020

We particularly welcome applications from black and minority ethnic candidates as they are under-represented within UCL at this level. 

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