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UK DRI King's College and Cambridge Cross-Centre Postdoctoral Research Associate

King's College London - UK DRI in Basic and Clinical Neuroscience

Location: London
Salary: £38,304 to £40,414 including London Weighting Allowance
Hours: Full Time
Contract Type: Fixed-Term/Contract
Placed On: 16th October 2020
Closes: 15th November 2020
Job Ref: R6/1336/20-KM
 

UK DRI in Basic and Clinical Neuroscience

Dementia is the greatest health challenge of our century. 

Researchers at the UK Dementia Research Instiute at King’s College London are using innovative approaches to explore the biological mechanisms involved in neurodegenerative diseases. Their goal is to defeat dementia by uncovering vital new knowledge that will lead to the design of smarter diagnostics and effective treatments. The team aims to understand the fundamental biological processes involved in dementia at a molecular level – and to use that knowledge to design new ways to diagnose and treat disease more precisely. 

The UK Dementia  Research Institute (DRI) groups of PD Dr Marc-David Ruepp (UK DRI at King’s College London) and Prof Giovanna Mallucci (UK DRI at Cambridge) and are seeking a Postdoctoral Research Associate for a 3-year collaborative project. The UK DRI is a national consortium focused on cutting-edge dementia research funded by the Medical Research Council, Alzheimer’s Society and Alzheimer’s Research UK (www.ukdri.co.uk). 

The project aims at characterising the physiological and neuroprotective roles of the RNA  binding  protein RBM3, key to the cold shock response. The postdoctoral research associate will start with the characterisation and validation of the RBM3 RNA and protein interactomes in the group of Marc-David Ruepp at King’s College London (https://ukdri.ac.uk/team/marc-david-ruepp), followed by cellular and in vivo validation experiments of key candidate interactors in the group of Giovanna Mallucci at Cambridge University (https://ukdri.ac.uk/team/giovanna-mallucci).  

We are looking for a candidate with good knowledge in molecular biology/biochemistry, RNA biology and mammalian cell culture that is keen to work across the King’s College London and University of Cambridge UK DRI centres. In vivo experience in mice is desireable but not essential at this stage   

Key responsibilities 

  • Investigate research questions under guidance from the Group Leaders 
  • Finding innovative solutions to problems and developing novel lines of research 
  • Provide significant contribution to the production of research papers in high impact journals 
  • Work in a collaborative manner, sharing knowledge and expertise within the team, department and with collaborators 
  • Presenting findings at internal and external meetings and conferences 
  • Contribute to the training and supervision of junior staff 
  • Be committed to own personal career development 
  • Undertake any other reasonable duties that may be requested by the PIs. 

The above list of responsibilities may not be exhaustive, and the post holder will be required to undertake such tasks and responsibilities as may reasonably be expected within the scope and grading of the post.  

Contact email address for informal enquiries about the role:

Marc-David Ruepp (King's College), marc-david.ruepp@kcl.ac.uk 

Giovanna Mallucci (Cambridge), gm522@cam.ac.uk 

 

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