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Research Technician in Epigenetics of Neurobiology (MED02287)

Imperial College London

Location: London
Salary: £29,738 to £32,593 per annum
Hours: Full Time
Contract Type: Fixed-Term/Contract
Placed On: 23rd February 2021
Closes: 22nd March 2021
Job Ref: MED02287

Location: White City Campus

Job Summary:

Dementia is the greatest health challenge of our century.

To date there is no way to prevent it or even slow its progression, and there is an urgent need to fill the knowledge gap in our basic understanding of the diseases that cause it.

The UK Dementia Research Institute (UK DRI) is the biggest UK initiative driving forward research to fill this gap.

The UK DRI at Imperial brings together researchers from diverse backgrounds with fresh perspectives, drawing on the university’s unique strengths, resources and focus on science, engineering, medicine and business. The team recognises that the challenges of dementia demand new concepts, new approaches and a diverse range of new research tools and directions. Their holistic approach views the ageing brain in the context of the ageing body, not in isolation.

Duties and responsibilities
In this role, you will support a growing research team in the UK DRI Centre at Imperial with technical support for single cell epigenetics in neurodegenerative diseases. For example, you will support the development of new methods for enriching nuclei of rare cell types from post-mortem human brain. This will involve testing of new antibodies, as well as cutting edge methods for fluorescent sorting based on RNA. You will also be involved in developing, scaling up and applying new plate-based single-cell genomic methods. This project will involve working with human tissue brain banks and will be involved in sourcing and validating the samples.

You will work within a mission-focused team of experimental and computational biologists as well as collaborating with neuropathologists and brain banks. Our centre of the UK DRI has made a strong commitment to neurogenomics and epigenetics, providing a critical mass of closely collaborating research groups. In addition to research support, the duties will include laboratory administrative responsibilities. 

Essential requirements

  • A qualification in relevant laboratory sciences, biology, one of the biomedical or related sciences or equivalent vocational qualification or relevant laboratory-based experience
  • Experience in laboratory-based research
  • Practical experience with genomics methods and biological tissue management
  • Computer literacy using Microsoft Word, Excel and PowerPoint

Further information

This post is offered as a Full time and Fixed term of 2 years, with potential for extension. 

You will be working in the new Sir Michael Uren Hub, White City Campus with access to resources in the Department of Brain Sciences with research labs in the Burlington Danes Building of Hammersmith Campus.

Should you have any queries please contact Dr Nathan Skene,

For technical issues when applying online please email

Job Ref number: MED02287

Closing Date: 22nd March 2021

Committed to equality and valuing diversity, we are an Athena SWAN Silver Award winner, a Stonewall Diversity Champion, a Disability Confident Employer and work in partnership with GIRES to promote respect for trans people

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