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Research Associate

Newcastle University

Location: Newcastle upon Tyne
Salary: £30,942 to £38,017 per annum
Hours: Full Time
Contract Type: Fixed-Term/Contract
Placed On: 11th June 2021
Closes: 11th July 2021
Job Ref: 8863

Company Description

We are a world class research-intensive university. We deliver teaching and learning of the highest quality. We play a leading role in economic, social and cultural development of the North East of England. Attracting and retaining high-calibre people is fundamental to our continued success.

The Role

You will be part of a team based in the Newcastle Cancer Centre that will use structural, chemical and cell biological tools to understand the roles and mechanisms of CDKs to generate hypotheses for drug discovery. You will use contemporary structural, biochemical, and biophysical techniques to characterise CDK complexes involved in the control of the eukaryotic cell cycle and the regulation of transcription. We are looking for an accomplished researcher with experience in inter-disciplinary protein structure determination and expertise in contemporary structural biology techniques, with a requirement for familiarity with cryo electron microscopy and X-ray crystallography. You will design, implement and deliver novel strategies to prepare protein complexes. You should have experience in contemporary techniques in high throughput protein crystallography for inhibitor design. You will also have experience in using biophysical techniques to characterise protein structure, function and regulation. You will work within a large multi-disciplinary team that includes biologists, structural biologists and chemists.

The position is funded by the Medical Research Council, and is available on a fixed term basis for 5 years, available from 1st August 2021.

Informal approaches can be made via email to Professor Jane Endicott (jane.endicott@ncl.ac.uk) or Professor Martin Noble (martin.noble@ncl.ac.uk)

Information about the Cell Cycle Structural Biology Group can be found at: https://research.ncl.ac.uk/cellcyclestructuralbiology/

Information about the Faculty of Medical Sciences is available at: https://www.ncl.ac.uk/medicalsciences/

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