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Research Associate

King's College London - Physics/Randall

Location: London
Salary: £38,304 to £45,026 including London Weighting Allowance
Hours: Full Time
Contract Type: Fixed-Term/Contract
Placed On: 3rd September 2021
Closes: 30th September 2021
Job Ref: 030065
 

Campus: Strand/Crick

Contact: Sergi Garcia-Manyes, Sergi.garcia-manyes@kcl.ac.uk 

Job description 

We are seeking to appoint a physical scientist (preferably with a PhD in Physics or related disciplines) with experience on single molecule nanomechanical experiments applied to proteins. The project will investigate the nanomechanical properties of proteins forming the adherens junctions in epithelial and endothelial tissues. The candidate will join a multidisciplinary group in the Department of Physics of King’s College London working on several aspects of mechanosensing and mechanotransduction from the single molecule level. The project is part of the BBSRC sLOLA consortium, held between the University of Bristol, UCL and King’s College London (https://gtr.ukri.org/projects?ref=BB%2FV003518%2F1).

This post will be offered on an a fixed-term contract for 24 months (renewable)

This is a full-time post - 100% full time equivalent

Key responsibilities

  • Develop high quality research in the field of single protein mechanics
  • Contribute to publications arising from this project
  • Contribute fully to developing and enhancing the research profile of the Department, Faculty, and University, including establishing a track record of high quality publications
  • Use new research techniques and methods
  • Identify areas for research, develop new research methods and extend the research portfolio

The above list of responsibilities may not be exhaustive, and the post holder will be required to undertake such tasks and responsibilities as may reasonably be expected within the scope and grading of the post.

Skills, knowledge, and experience

Essential criteria

  • Hold a PhD in Physics, Biophysics, Physical Chemistry or equivalent
  • Experience with single molecule nanomechanical experiments (AFM/Magnetic Tweezers/Optical Tweezers).
  • Programming skills
  • Experience with instrument development
  • Experience in student supervision
  • Experience in grant writing and project design

Desirable criteria

  • Experience in light (especially confocal) microscopy
  • Experience in cell mechanobiology (AFM, tweezers, substrate stiffness…)
  • Experience in protein design, cloning, expression and purification
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