Single-cell analysis of planarian stem cell differentiation and regeneration.
The Solana lab seeks a computational researcher to develop projects on single-cell analysis of planarian and invertebrate stem cell differentiation. This position is funded by the BBSRC.
Single-cell sequencing methods are revolutionizing the study of stem cells. The flatworm Schmidtea mediterranea is a very promising model for in vivo stem cell biology thanks to its large number of stem cells that continuously differentiate to all adult cell types and that enable its amazing regenerative capacities. We have previously used single-cell transcriptomics to study stem cell differentiation in planarians. Combining clustering algorithms with graph mathematics and RNA metabolism information we were able to reconstruct the differentiation lineage tree of planarian stem cells.
The successful applicant will have a PhD or equivalent experience in genomic or transcriptomic analysis and must have good computational skills, including experience in R and Unix. Additionally, the applicant must have organisational and time management skills, and ability to work independently.
As one of the largest employers in Oxford we pride ourselves in the great experience we offer our staff. You’ll be joining a friendly, professional environment where every member of staff is recognised as important to the success of Oxford Brookes University. To find out more about the benefits of working for Oxford Brookes please visit: www.brookes.ac.uk/job-vacancies/working-at-brookes.
The University has adopted equality, diversity and inclusion as core values. We welcome applications from suitably qualified candidates whatever their background, and especially from BAME candidates who are under-represented in our workforce.
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