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Research Fellow: chemogenetic tools

UCL - Department of Clinical and Experimental Epilepsy

Location: London
Salary: £32,217 to £42,048
Hours: Full Time
Contract Type: Fixed-Term/Contract
Placed On: 9th November 2021
Closes: 1st December 2021
Job Ref: 1878528
 

Applications are invited for a Research Fellow in the Department of Clinical and Experimental Epilepsy, UCL Queen Square Institute of Neurology. The mission of the Department is to transform the lives of people living with epilepsy for the better by identifying, understanding and correcting or preventing the underlying mechanisms leading to the epilepsies and associated comorbidities in each individual person.

The post holder will design, optimize and validate molecular tools to manipulate the excitability of neurons and brain circuits. The project will advance fundamental neuroscience and the treatment of neurological and psychiatric disorders. It will feed into a programme of research into gene therapy for refractory epilepsy, with a view to clinical translation. It will be supervised by Professor D M Kullmann.

Applicants should have (or be close to obtaining) a PhD or equivalent in molecular or cellular neuroscience or a related discipline. Experience of molecular pharmacology, medicinal chemistry, molecular modelling, and/or cellular electrophysiology is essential, as is a deep understanding of G-protein coupled receptor signalling. Expertise in cell-based arrays, immunofluorescence and confocal microscopy, IT proficiency at advanced user level, excellent oral and written communication skills, good inter-personal skills with an ability to work co-operatively in a multidisciplinary setting, and strong problem-solving abilities are also required.   Experience of working with viral vectors is desirable.

The post is available immediately and is funded by a grant from the Medical Research Council to 31 March 2024 in the first instance.

Starting salary on UCL Grade 7 which ranges from £36,770 to £42,048 per annum (including London Allowance). Appointment at Grade 7 is dependent upon having been awarded a PhD; if this is not the case, initial appointment will be at research assistant Grade 6B (salary £32,217 - £33,958 per annum) with payment at Grade 7 being backdated to the date of final submission of the PhD thesis. If the PhD has not yet been granted, the final accepted version of the thesis must have been submitted to the degree-granting university by the start date in post.

You should apply for this post through UCL's online recruitment – www.ucl.ac.uk/hr/jobs where you can download a job description and person specification using reference: 1878528. 

If you have any queries regarding the application process, please contact Oksana Shapoval, HR Officer, UCL Queen Square Institute of Neurology (email: ion.hradmin@ucl.ac.uk).

Closing date:  1 December 2021

We will consider applications to work on a part-time, flexible and job share basis wherever possible.

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