Qualification Type: | PhD |
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Location: | Guildford |
Funding for: | UK Students |
Funding amount: | £16,062 to £17,040 Stipend amount, per annum |
Hours: | Full Time |
Placed On: | 30th November 2022 |
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Closes: | 28th February 2023 |
Reference: | PGR-2223-017 |
PhD Studentship: Electromagnetic (EM) fields to modulate Purkinje cell activity for treatment of Parkinson's disease
Parkinson’s disease (PD) is a debilitating neurological disorder that affects 137,000 people in the UK. Its cause and pathogenesis is uncertain but recent studies in mice have demonstrated that misfiring of Purkinje cell in the brain cerebellum generates high-amplitude tremors that are corrected by the application of electromagnetic fields (EMFs)1 to Purkinje cells via deep brain stimulation (DBS). Previous work in our laboratory supported by the Astor Foundation demonstrated that electromagnetic (EM) field effects on cells are mediated through changes in calcium homeostasis. This PhD student will extend this approach to investigate the effect of EM field on Purkinje cells with the long-term aim of developing novel therapies for Parkinson’s Disease. The project will be supervised by Patrizia Camelliti and Johnjoe McFadden.
Entry requirements
Open to UK students starting in April 2023. Later start date is also possible.
You will need to meet the minimum entry requirements for our Quantum Biology PhD programme.
The successful student with have, or be expected to gain, a first or upper-second UG degree in Biomedical Sciences, Biochemistry or related subjects. We may also accept student with training in experimental Electrical Engineering or Medical Physics or related subjects.
How to apply
Applications should be submitted via the Quantum Biology PhD programme page. In place of a research proposal you should upload a document stating the title of the project that you wish to apply for and the name of the relevant supervisor.
Funding
The Stipend Amount are Year 1: £16,062; Year 2: £16,544; Year 3: £17,040. Funding is for 3 years.
This project is directly funded by John Jacob Astor Foundation.
Application deadline: 28th February 2023
Enquiries
Contact: Patrizia Camelliti..
Ref: PGR-2223-017
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