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Postdoctoral Research Associate in Membrane Protein Structural Biology

University of Oxford - Department of Biochemistry

Location: Oxford
Salary: £34,308 to £42,155 per annum. Grade 7
Hours: Full Time
Contract Type: Fixed-Term/Contract
Placed On: 8th December 2022
Closes: 6th January 2023
Job Ref: 162393

Location: Department of Biochemistry, South Parks Road, Oxford             

We are seeking to appoint a Postdoctoral Research Associate to address specific questions about the molecular basis for amino acid transport in mammalian cells. The project is multidisciplinary, involving a range of structural, biochemical and biophysical approaches, including single-particle Cryo-EM, and biochemical and biophysical characterisation of membrane protein function. You will have primary responsibility for the project work, including planning and managing the research. You will contribute to the general smooth running of the laboratory and will be expected to help with training and teaching within the laboratory. 

Applicants should hold a PhD/DPhil, be near completion of a PhD/DPhil in Biochemistry/Structural Biology or related area and should have evidence of successful purification and structural studies with eukaryotic transporters. You will have experience in developing and using cell-based transport assays and evidence of biochemical studies on secondary transporters. Experience in single particle cryo-EM sample preparation and the use of relevant software is essential together with experience in biophysical analysis of ligand-protein interactions. You will have proven ability to independently analyse data and design biochemical assays to address important mechanistic questions, as well as evidence of using molecular dynamics. Good interpersonal and communication skills are expected.

This full-time fixed term post is funded by the Wellcome Trust for up to 12 months in the first instance and is based at the Department of Biochemistry, South Parks Road, Oxford. 

This position is graded on the University’s Grade 7 scale, for which the salary range is £34,308 - £42,155 per annum. The actual starting salary offered will be based on qualifications and relevant skills acquired and will also be determined by the funding available.

To apply for this role and for further details including the job description and selection criteria, please see the document below. You will be required to upload a supporting statement and CV as part of your application.

The closing date for applications is 12.00 noon on Friday 6th January 2023, with interviews for shortlisted candidates to be held as soon as possible thereafter.

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