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Postdoctoral Fellow

European Molecular Biology Laboratory (EMBL)

About the team/job

EMBL is Europe’s flagship laboratory for the life sciences – an intergovernmental organisation with more than 110 independent research groups and service teams covering the spectrum of molecular biology. It operates across six sites in Heidelberg (headquarters), Barcelona, Cambridge, Grenoble, Hamburg and Rome. Our mission is to perform basic research in molecular biology; train scientists, students and visitors at all levels; offer vital services to scientists in the public and private sectors within the member states; develop new instruments and methods; and engage actively in technology transfer.

The Savitski group at EMBL Heidelberg is seeking a postdoc with a proteomics/biochemistry background to work on applying functional proteomics methods to study the mechanism behind protein aging in vivo. In particular, the candidate will work on combining Thermal Proteome Profiling (TPP), Solubility Proteome Profiling (SPP), protein turnover analysis and extensive post-translational modification analysis to understand the mechanisms of protein aging. 

Your role

Establish protein extraction protocols from mouse tissue, and apply a variety of functional assays, including TPP, SPP and PTM enrichment. Develop an analysis strategy for determination of protein turnover in different tissues. 

You have

  • PhD in proteomics/biochemistry or related fields.
  • Experience with protein extraction from tissue or cells.
  • High organization skills (handling a large number of samples).
  • Familiarity with working with large datasets, ideally in R.
  • A keen interest in biological applications.
  • Be able to work independently, reliable and enjoy working in an international team within a highly collaborative atmosphere.
  • Excellent communication and presentation skills, a high level of motivation and fluency in English are required. 

You might also have

Experience with sample preparation methods for mass spectrometry. 

Why join us

EMBL is curiosity-driven, community-oriented and international. As an inclusive, equal opportunity employer, we believe that diversity enables us to collaborate more effectively and be innovative in our approaches. We are, therefore, committed to creating an inclusive and flexible culture - one where everyone can realise their full potential and make a positive contribution to our organisation. 

We encourage applications from individuals who can complement our existing team – we believe that success is built on having teams whose backgrounds and personal experiences reflect the diversity of the populations that our science serves. We actively encourage applications from all genders and cultures, ethnic groups and all demographics to help us avoid perpetuating biases and oversights at this transformational point in our people strategy.

EMBL offers attractive conditions and benefits appropriate to an international research organisation with a very collegial and family-friendly working environment. Competitive salary and social security benefits, financial support for relocation, a relaxed culture, professional development, an on-site nursery, canteen and other staff facilities make EMBL a great place to work. 

What else you need to know

We are Europe’s flagship research laboratory for the life sciences – an intergovernmental organisation performing scientific research in disciplines including molecular biology, physics, chemistry and computer science. We are an international, innovative and interdisciplinary laboratory with more than 1900 employees from many nations, operating across six sites, in Heidelberg (HQ), Barcelona, Hinxton near Cambridge, Hamburg, Grenoble and Rome.

Our mission is to offer vital services in training scientists, students and visitors at all levels; to develop new instruments and methods in the life sciences and actively engage in technology transfer activities, and to integrate European life science research. The working language of the institute is English.

The initial contract is for a period of two years with the possibility of a fixed-term extension.

EMBL is a signatory of DORA. Find out how we implement best practices in research assessment in our recruitment processes here.

Please apply online, by clicking the 'Apply' button.

Location: Heidelberg - Germany
Salary: Stipend
Hours: Full Time
Contract Type: Fixed-Term/Contract
Placed On: 23rd January 2023
Closes: 6th March 2023
Job Ref: HD02362
 
   
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