Research Associate

Location: Royal Brompton Campus

Job Summary

The Margaret Turner Warwick Centre for Fibrosing Lung Disease at the National Heart and Lung Institute is seeking a highly motivated Post-Doctoral Research Associate with experience in developing cell culture models, confocal imaging and image analysis and an interest in developing a non-animal model of the lung for analysis of senescence-associated cellular cross talk.

The post is jointly funded by the NC3Rs and BBSRC through the development of next generation non-animal technologies call. You will develop a complex, multicellular human 3D lung organoid with the capability to report activation of multiple cell signalling pathways simultaneously in real time. You will also work closely with imaging scientists in the Facility for Imaging by Light Microscopy (FILM) and data scientists within the MTW Centre to develop the analysis tools to understand the temporospatial dynamics of the cell signalling pathways involved in the acquisition of cellular senescence.

This is an exciting and challenging project that will give you the opportunity to join a well-funded and established research group consisting of research scientists, PhD students, clinicians and data scientists based within the NHLI at the only Centre for Fibrosing Lung Disease in the UK.

Duties and responsibilities

• To prioritise, plan and conduct research within project timelines
• To maintain highly organised and accurate records of all experimental work.
• To perform data analysis, ensuring the validity and reliability of data at all times
• To report findings at weekly lab group meetings
• Show willingness to work out of normal working hours (including weekends) if the requirements of the project demand.
• To undertake training in any new techniques that may be required during the project
• To write reports for submission to research sponsors
• To publish in high quality journals and to present data at national and international conferences.
• To assist in the supervision of students or researchers as required.
• To contribute to the smooth running of the laboratories and core facilities.

Essential requirements

• Research Associate: Hold a PhD (or equivalent) in Biological Sciences or a closely related discipline.
• Research Assistant: Near completion of a PhD (or equivalent) in Biological Sciences or a closely related discipline or a closely related discipline
• Practical experience within a research environment
• Practical experience in cell culture, confocal imaging, and image analysis
• Ability to prioritise, plan ahead and manage a high volume of work.
• Proven skills at problem-solving, overcoming obstacles and using initiative.
• Ability to work under pressure while maintaining a high degree of accuracy.

Further information

This is a Full Time and Fixed Term post until April 2024 and will be based at the Royal Brompton Campus in London.

Candidates who have not yet been officially awarded their PhD will be appointed as a Research Assistant within the salary range £38,194 - £41,388 per annum.

Should the candidates require any further details on the role please contact: Dr Alison John – a. john@imperial.ac.uk

Closing date: 07 Feb 2023

To apply, visit www.imperial.ac.uk/jobs and search by the job reference MED03640.

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