Research Fellow in Biochemistry and Quantitative Cell Biology (101445-0223) (Two Posts)

2 x Fixed-term contract for 2 years with possibility for extension until end of 2027, 1.0 FTE.

Two Wellcome-funded postdoctoral positions are available in the Straube lab to investigate how molecular motors dynein and KIF1C organise microtubule arrays and transport intracellular cargoes. The project will combine the generation of cell lines, live cell imaging (using spinning disk and lattice light sheet microscopy), in vitro reconstitution and single molecule biophysics (using TIRF imaging and optical trapping) to understand how these motors switch between their roles as cargo transporters and microtubule organisers.

The post holders will be members of the Centre for Mechanochemical Cell Biology and Warwick Medical School benefitting from an outstanding scientific environment and access to state-of-the-art research facilities.

Informal enquiries including a CV should be sent to a.straube@warwick.ac.uk.

You will join the laboratory of Dr Anne Straube in the Centre for Mechanochemical Cell Biology. The Straube lab aims to understand how microtubule arrays are organised and control the morphology of cells. In particular we use live cell imaging, force measurements, quantitative image analysis tools and in vitro reconstitution experiments to understand the function of motor proteins in organising microtubules and transporting cargo. We offer an outstanding environment for discovery science in one of the best universities in the UK.

The posts are funded by a Wellcome Investigator Award to investigate how cargo transporters organise the tracks along which they transport cargoes. You will be part of an international, well-resourced team of researchers with access to state-of-the-art equipment (including access to a range of light microscopy systems including spinning disk confocal, TIRF, lattice light sheet and optical tweezers) and a vibrant scientific community with excellent internal and external seminar programmes.

You will have an excellent first degree in a relevant subject area (biochemistry, biological sciences, biophysics etc.), have or expect shortly to complete a PhD or have equivalent research experience. Experience in working on an interdisciplinary scientific project is desirable, strong scientific interest and motivation are essential.

If you are near submission or have recently submitted your PhD but have not yet had it conferred, any offers of employment will be made as Research Assistant at the top of level 5 of the University grade structure (£31,411). Upon receipt of evidence of the successful award of your PhD, you will be promoted to Research Fellow on the first point of level 6 of the University grade structure (£32,348).

Please note we reserve the right to close this advert early should a suitable candidate be found, so please don’t delay in submitting your application.

Interview Date: TBC.

Full details of the duties and selection criteria for this role can be found in the vacancy advert on the University of Warwick's jobs pages. You will be routed to this when you click on the Apply button.

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