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Research Associate - Cancer Research

University of Sheffield - School of Medicine and Population Health

Location: Sheffield
Salary: £37,099 to £45,585 per annum (Grade 7)
Hours: Full Time
Contract Type: Fixed-Term/Contract
Placed On: 11th June 2024
Closes: 30th June 2024
Job Ref: UOS041242

Faculty:

Faculty of Health

Department:

Division of Clinical Medicine

School of Medicine and Population Health

Contract type: 

Fixed term until 31st August 2027

Location:

School of Medicine and Population Health
Beech Hill Rd
Sheffield
S10 2RX

We have an exciting opportunity, which is perfect for a researcher with a passion for driving biological discoveries through to development of new cancer therapeutics. It is ideally suited to an enthusiastic researcher looking to use their skills in cancer biology, bone biology, cancer cell dormancy, translational research and/or relevant fields who want to have an impact on patients with incurable cancers that have spread in bone (beginning with advanced breast and prostate cancer). 

You will join the School of Medicine and Population Health at The University of Sheffield, and become a member of the Cancer and Bone (CAB) Lab, led by Dr Alanna Green. The CAB Lab is within the Division of Clinical Medicine and the University-wide interdisciplinary Cancer Research Network and Mellanby Centre for Musculoskeletal Research. We have a diverse work environment that is world-leading for bone oncology, with a strong history of taking discoveries from the lab through to the clinic. Our team uses innovative models and techniques to investigate the mechanisms that enable cancer cells to evade chemotherapy, including the role of the bone microenvironment. We publish our work in leading journals and conferences in the field, and have taken our discoveries in the lab through to clinical trials. You will be supported with a number of career development opportunities, including applying for fellowships. 

We are seeking an enthusiastic and motivated researcher to work on the first phase of a 5-year Yorkshire Cancer Research-funded award. The project will investigate how dormancy allows cancer cells to evade chemotherapy and identify weaknesses of dormant cell to enable us to develop new dormancy-targeting therapeutics. You will use clinically-relevant in vitro (2D/3D) and in vivo models of cancer dormancy and chemotherapy-resistance. You will test new dormancy and niche-targeting therapeutic approaches to kill dormant cancer cells, and interrogate new dormancy targets under investigation in our lab. You will be based at The University of Sheffield and liaise with international collaborators at the Luxembourg Institute of Health, Karolinska Institute, Sweden, the Garvan Institute, Australia and industrial partners Oxcia AB. 

This is a 3-year post, with potential to extend to 2029. We are committed to exploring flexible working opportunities which benefit the individual and University. 

Apply now by clicking on the Apply button located near the top of your screen.

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