Research Fellow - Exploiting Chromatin Defects to Detect and Target Cancer

Hours: Full time or part time hours considered up to a maximum of 1.0 FTE. Requests for flexible working options will be considered (subject to business need)
Location: Brighton, United Kingdom
Contract: Fixed Term to 31 March 2027
Expected Interview date: To be confirmed
Expected start date: September 2024

Exploiting chromatin defects to detect and target cancer

Motivated applicants are invited to apply for an MRC-funded full-time postdoctoral research position within the Humphrey lab at the Genome Damage and Stability Centre, University of Sussex. Chromatin modifiers are frequently mutated in a broad spectrum of cancers, identifying them as important cancer targets. Using a powerful combination of molecular genetics, immunohistochemistry and bioinformatics we are exploring how the DNA damage response can be exploited to target chromatin-modification defects associated with particular cancer types. The successful candidate will be expected to work both independently and as part of a team; to have regular meetings with their supervisor; to discuss their work at regular lab meetings; to present their work nationally/ internationally, and to publish their results in a timely manner.

Required qualifications for this position:

• Hold (or be near to completing) a PhD in a related subject.
• First author publication(s) in a reputable journal.
• Fluent in written /spoken English with excellent writing skills.
• Expertise in relevant techniques.
• Commitment to work in a highly competitive field.
• Ability to work independently and as part of a team.

Potential candidates are strongly encouraged to make informal contact with Prof. Timothy Humphrey (timothy.humphrey@sussex.ac.uk) before applying.

Based in the School of Life Sciences, the Genome Damage and Stability Centre  (http://www.sussex.ac.uk/gdsc/), is an internationally renowned Institute carrying out research on the response of cells to DNA damage, genome instability and its relationship to disease. We provide a stimulating and supportive environment and our expertise covers a range of experimental systems.

The School of Life Sciences is committed to increasing the diversity of its staff and providing an inclusive working environment. The School currently holds an Athena SWAN Silver Award, has developed a Race Equity Action Plan and hosts an active Equality, Diversity and Inclusion working group.

Applications are particularly welcomed from Black and minority ethnic candidates, and women, trans and non-binary candidates, who are under-represented in the School of Life Sciences.

Applications to posts from candidates who wish to work part-time or as job-sharers are welcome.

The University offers various schemes to provide real benefits to parents, these can be found at Family Friendly Policies

Applications should be accompanied by a full CV, a statement of research interests and aspirations (not more than 4 pages), and the names of three academic referees. [Optional

“Please note that this position may be subject to ATAS clearance if you require visa sponsorship.”

For full details and how to apply please click on apply button. 

The University of Sussex values the diversity of its staff and students and we welcome applicants from all backgrounds.

Please note: The University requires that work undertaken for the University is performed from the UK. 

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