Research Associate

Role Description

Department and Research group

Applications are invited for a full-time postdoctoral research associate, to join the research group of Dr. Mihaela Lorger. A successful candidate will work on an MRC-funded project to elucidate the role of dendritic cells in brain metastases, with the aim to identify strategies that can potentiate the efficacy of immunotherapy in the brain. Dr. Lorger’s research group is located at the University of Leeds and at the University of York.

This project will be based in the Department of Biology at the University of York.

Role

You will pursue a project aimed at understanding how dendritic cells contribute to anti-tumour immune response and the control of tumour growth in brain metastases, including in the context of immune checkpoint blockade. To this end, you will be studying dendritic cell-dependent anti-tumour immune responses at the cellular and molecular level, integrating findings from molecular profiling, functional ex vivo assays, in vivo studies in preclinical models of brain metastases, followed by validation of findings in human brain metastases tissue.

Funding is available for up to 30 months.

Skills, Experience & Qualification needed

• First degree in biology or related discipline
• PhD in biology, biomedical sciences, immunology, or equivalent experience
• Home office personal licence specifying rodents (or equivalent if not from the UK)
• Knowledge in immunology and a range of related research techniques and methodologies
• Hands-on experience with in vivo models
• Excellent communication and presentation skills
• Ability to work flexible hours to accommodate the requirements of the project
• Knowledge in cancer biology, neuroscience and/or dendritic cell biology is desirable

Interview date: To be confirmed

For informal enquiries: please contact biol-dmthub@york.ac.uk or mihaela.lorger@york.ac.uk

The University strives to be diverse and inclusive – a place where we can ALL be ourselves.

We particularly encourage applications from people who identify as Black, Asian or from a Minority Ethnic background, who are underrepresented at the University.

We offer family friendly, flexible working arrangements, with forums and inclusive facilities to support our staff. #EqualityatYork

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