Principal Laboratory Research Scientist – Sateriale Lab

Short summary

Dr Sateriale’s group was established at the Francis Crick in 2020, with the expressed goal of understanding the molecular mechanisms that govern infection and immunity for apicomplexan parasites, a group of pathogens that are represent a significant burden on public health.

In the lab, we use a variety of in vitro and in vivo models to mimic human infection, with the goal of broadening the foundation of knowledge that can be leveraged to develop new interventions. Common techniques used in the lab include: genetic engineering, flow cytometry, expansion and super-resolution microscopy, immunofluorescence and immunoprecipitation, high-throughput screening and sequencing.

The Role

This role forms an important position in the EPSRC funded Prosperity Partnership with GSK, an academic/industry strategic partnership which is aiming to develop systems chemical biology approaches to identify chemical tools to dissect biological pathways and identify potentially tractable therapeutic targets in a range of disease setting including malaria and cryptosporidiosis. As such, the position will involve working with scientists from both GSK and Dr Adam Sateriale’s group at the Francis Crick Institute.

Key Responsibilities

• Independently leading multiple research projects, designing, and executing experiments with strategic direction from the group leader.
• Presenting results group meetings, journal clubs, seminars, and scientific meetings.
• Writing up findings for publication and completing revisions.
• Organisation and management of the laboratory, including maintaining laboratory databases, ordering of laboratory supplies, monitoring budgets, and routine maintenance of laboratory equipment. 
• Training and supervising other lab members in key techniques and protocols, lab operations, and equipment use.
• Liaising with Science Operations and attending key quadrant meetings.
• Writing risk assessments and SOPs and providing safety guidance to lab members.
• Collaborating and assisting other lab members with research projects.

About us

The Francis Crick Institute is a biomedical discovery institute dedicated to understanding the fundamental biology underlying health and disease. Its work is helping to understand why disease develops and to translate discoveries into new ways to prevent, diagnose and treat illnesses such as cancer, heart disease, stroke, infections, and neurodegenerative diseases.

An independent organisation, its founding partners are the Medical Research Council (MRC), Cancer Research UK, Wellcome, UCL (University College London), Imperial College London and King’s College London.

The Crick was formed in 2015, and in 2016 it moved into a new state-of-the-art building in central London which brings together 1500 scientists and support staff working collaboratively across disciplines, making it the biggest biomedical research facility under in one building in Europe.

The Francis Crick Institute will be world-class with a strong national role. Its distinctive vision for excellence includes commitments to collaboration; developing emerging talent and exporting it the rest of the UK; public engagement; and helping turn discoveries into treatments as quickly as possible to improve lives and strengthen the economy.

• If you are interested in applying for this role, please apply via the ‘Apply’ button above.
• All offers of employment are subject to successful security screening and continuous eligibility to work in the United Kingdom.

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