Location: | Swansea |
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Salary: | £37,099 per annum |
Hours: | Full Time |
Contract Type: | Fixed-Term/Contract |
Placed On: | 20th August 2024 |
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Closes: | 9th September 2024 |
Job Ref: | SU00494 |
Location: Singleton Campus, Swansea
About The Role
This is a Full Time, Fixed Term position until 30/09/2026.
A postdoctoral researcher is required (for a total period of 24 months) to conduct research on the Cancer Research Wales Pritchard and Moore Scholarship “New radiosensitizers for triple-negative breast cancer”. Research will be performed primarily at Swansea University, Department of Chemistry, and the project will include a 6 month placement at Bangor University, School of Medical Sciences. The project will also involve working closely with collaborators at the University of Oxford, Department of Oncology.
The role requires the synthesis and characterisation of metallo-drug candidates, their evaluation as enzymatic inhibitors, and the evaluation of their therapeutic potential in cancer cell lines, including alongside ionizing radiation (IR) to identify novel radiosensitizers. This will involve working with researchers from a range of disciplines, including chemists, cell biologists and medical scientists.
Small molecule synthesis, enzyme inhibition and non-IR cell-based assays will be conducted at Swansea University, Department of Chemistry, while a placement in Bangor University, School of Medical Sciences, will provide the candidate with a fantastic opportunity to undertake advanced immunofluorescent assays alongside IR studies.
The successful candidate should hold an advanced degree in chemistry, medicinal chemistry or a related subject and have a keen desire to undertake research at the chemistry/biology/medicine interface. Experience of small molecule synthesis in addition to cell culture techniques are required, while further training in cell-based assays and bio-assays will be provided.
Please email Dr Martin Gill m.r.gill@swansea.ac.uk or Dr Chris Staples c.staples@bangor.ac.uk for informal enquiries.
Equality, Diversity & Inclusion
The University is committed to supporting and promoting equality and diversity in all its practices and activities. We aim to establish an inclusive environment and welcome diverse applications from the following protected characteristics: age, disability, gender reassignment, marriage and civil partnership, pregnancy and maternity, race (including colour, nationality, ethnic and national origin), religion or belief, sex, sexual orientation.
As an inclusive and welcoming workplace, we value people for their skills regardless of their background. Applications are welcome in Welsh and will not be treated less favourably than those submitted in English.
We have an under-representation of women and ethnic minority colleagues in academia and would particularly encourage applications from these groups. Appointments will always be made on merit.
Welsh Language Skills
The Welsh language level required for this role is Level 1 - A little. The role holder will be able to pronounce Welsh words, answer the phone in Welsh (good morning/afternoon) and use very basic everyday words and phrases (thank you, please etc.). Level 1 can be reached by completing a 1 hour course.
The University is a proud bilingual institution, our Welsh Language Strategy outlines our aspiration to promote the language and enable our staff to engage with the language as an additional workplace skill and as a gateway to new cultural and social opportunities. Applications are welcome in Welsh and will not be treated less favourably than those submitted in English. Welsh speakers have the right to an interview in Welsh. Applicants for a role where Welsh skills are essential are expected to present their application in Welsh and will be interviewed in Welsh, if shortlisted.
Additional Information
Applications for this role will take the format of a CV submission and cover letter.
Closing Date: 9 September 2024
Interview Date: 18 September 2024
Informal Enquiries: Martin Gill m.r.gill@swansea.ac.uk
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