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Postdoctoral Researcher in Mass Spectrometry and Structural Proteomics

University of Oxford - Nuffield Department of Medicine

Location: Oxford
Salary: £36,024 to £44,263 with a discretionary range to £48,350 p.a. Grade 7
Hours: Full Time
Contract Type: Fixed-Term/Contract
Placed On: 22nd August 2024
Closes: 20th September 2024
Job Ref: 174957

Location:  - Centre for Medicines Discovery, NDM Research Building, Old Road Campus, Headington, Oxford, OX3 7FZ

We are seeking a highly-motivated Postdoctoral Researcher in biochemistry, proteomics and biological mass spectrometry (MS) in the Structural & Mechanistic Proteomics Laboratory of the Centre for Medicines Discovery (CMD), Nuffield Department of Medicine, University of Oxford. 

Your primary responsibility will be to develop and establish cutting-edge structural proteomics workflows, including HDX-MS for drug discovery and protein target characterisation. You will operate advanced liquid chromatography and MS equipment, with the ability to keep abreast of advances in the field and analyse complex and detailed proteomic datasets and develop novel research ideas which are generated from such datasets, and which may build upon current understanding. Other responsibilities include adapting existing and developing new scientific techniques and experimental protocols, carrying out collaborative projects with colleagues in partner institutions and research groups and contributing ideas for new research projects. 

It is essential that you hold a PhD/DPhil (or be close to completion) in Biochemistry, Biology or Analytical Chemistry, together with practical experience in HDX-MS and structural proteomics. You will have experience in designing and implementing proteomics experiments, and also with sample preparation workflows for MS analysis. You will possess the knowledge of operating HPLC and mass spectrometer systems, and up-to-date knowledge of current literature and research in biochemistry, proteomics and biological MS. 

Applications for this vacancy are to be made online and you will be required to upload a supporting statement and CV as part of your online application. Your supporting statement must explain how you meet each of the selection criteria for the post using examples of your skills and experience.   

This position is offered full time on a fixed term contract for 2 years in the first instance and is funded by the Department. 

Only applications received before 12 midday on Friday 20 September 2024 will be considered. Interviews to be held the week commencing 7 October 2024. Please quote 174957 on all correspondence.

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