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Correlative Imaging Scientist

University of Leeds - Faculty of Biological Sciences - School of Molecular & Cellular Biology - Astbury Centre for Structural Molecular Biology

Location: Leeds
Salary: £41,064 to £48,822 per annum (Grade 7)
Hours: Full Time
Contract Type: Permanent
Placed On: 7th August 2025
Closes: 7th September 2025
Job Ref: FBSAS1083
Location: Leeds - Main Campus

Are you a creative postdoctoral-scientist keen to explore novel in-situ biology with cryogenic electron tomography? Do you have a background in imaging technologies and/or image processing?

We are looking for a correlative imaging scientist to develop, innovate, and support in-situ structural biology workflows working across the Cheney Biomedical Accelerator and Astbury Biostructure Laboratory. Primarily, this role will support projects using (cryo) FIB-SEM, (cryo) confocal, and (cryo) TEM workflows to prepare organisms, tissues, and cells for cryogenic electron tomography.

Day to day, the role will involve working with multiple projects, training and assisting users, and working as part of the EM facilities team to maintain equipment and provide expert support and advice for both internal and external academics. You will be part of a supportive environment and be self-driven to further your own professional development whilst mentoring others. In addition, you will work collaboratively with the wider FBS facilities, specifically the Bio-imaging facility to support a cryo-CLEM user base.

The Astbury Biostructure Laboratory electron microscopy facility is a centre of excellence for structural biology, with expertise in both single particle cryoEM and tomography, and state of the art equipment: 

  • 2x Titan Krios microscopes (each with Falcon 4i and selectris)
  • A Talos L120C TEM
  • A Hydra Bio plasma FIB-SEM
  • A UC7 cryo-ultramicrotome
  • An EM ICE high pressure freezer
  • A Leica EM GP plunge freezer
  • A cryo confocal fluorescent microscope

You should have a PhD, significant experience with cutting edge imaging technologies, and a passion for studying biochemical processes. You should be motivated to work with many different imaging technologies, bringing experience in either cryoEM or fluorescent imaging, or both.

Salary Requirements of the Skilled Worker Visa Route

Please note that this post may be suitable for sponsorship under the Skilled Worker visa route, but first-time applicants might need to qualify for salary concessions. For more information please visit: www.gov.uk/skilled-worker-visa.

For research and academic posts, we will consider eligibility under the Global Talent visa. For more information please visit: www.gov.uk/global-talent.

To explore the post further or for any queries you may have, please contact:

Dr Tom O’Sullivan – Correlative Imaging Scientist

Email: t.j.osullivan@leeds.ac.uk

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