Technician

Job description:

Applications are invited for the post of Technician to join Sheffield’s Viral Immunotherapy for Bone Efficacy (VIBE) lab led by Dr Faith Howard based within School of Medicine and Population Health at the University of Sheffield’s Medical School. The overarching research goal of the VIBE team is to leverage drug delivery systems for the development of new bone targeted virotherapies.

More information on the Howard laboratories can be found here: https://sheffield.ac.uk/smph/people/academic/clinical-medicine/faith-howard

We are seeking a highly motivated, practically skilled, well organised and semi-independent individual to work on a 1-year PCR/BCN-funded project. We aim to synthesise nanoparticles to carry viral payloads to metastatic tumours using bone-tropic guidance strategies. We will evaluate nanoparticle properties, toxicity and efficacy in in vitro and in vivo models of prostate cancer metastasis to bone. By doing so, we will pave the way for targeted virotherapy delivery against currently incurable cancers.

You will be a practically skilled, well organised, flexible and committed Technician who will join an emerging laboratory team to conduct laboratory research on a semi-independent basis under the direction of Dr. Howard and project collaborators. You will be expected to; design, execute and evaluate experiments; keep excellent experimental records; prepare reports regularly and feed back to other members of the research group. You are also expected to contribute to the preparation of scientific manuscripts, attend and deliver seminars/lab meetings, help supervise undergraduate students and advise post-graduate research students as necessary as part of a collaborative research team. The successful candidate should be strongly motivated, self-driven, able to accept direction and be an excellent team player. Excellent communication and interpersonal skills are expected. You should have a degree relevant to the fields of drug delivery or bioengineering or have appropriate equivalent experience. You will have experience in human cell culture growth and manipulation, oncolytic virus amplification, immunohistochemistry/immunofluorescence, cell survival assays and murine cancer models. Expertise in molecular biology and immunology would be advantageous, but not necessary.

The School of Medicine and Population Health brings together researchers to translate scientific discoveries into clinically meaningful advances. More information about the School can be found here: https://www.sheffield.ac.uk/smph.

What We Offer:

The University of Sheffield is a remarkable place to work. Our people are at the heart of everything we do. Their diverse backgrounds, abilities and beliefs make Sheffield a world-class university.

We offer a fantastic range of benefits including a highly competitive annual leave entitlement (with the ability to purchase more), a generous pensions scheme, flexible working opportunities, a commitment to your development and wellbeing, a wide range of retail discounts, and much more.

Find out more at sheffield.ac.uk/jobs/benefits and join us to become part of something special.

We are committed to exploring flexible working opportunities which benefit the individual and University.

We build teams of people from different heritages and lifestyles from across the world, whose talent and contributions complement each other to greatest effect. We believe diversity in all its forms delivers greater impact through research, teaching and student experience.

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