King's College London

PhD Studentship Oct 2010

Pharyngeal Arch Development

King's College London

The pharynx has its developmental origin in a series of bulges found on the lateral surface of the embryonic head, the pharyngeal arches. The aim of this project is to define the mechanisms underpinning the early development of these key structures. We will use cellular and molecular analysis of chick and zebrafish embryos to address this issue. In particular, we will focus on the segmentation of the pharyngeal endoderm. This project will give us insights into normal development as well as shedding light on what goes wrong in human conditions which present with pharyngeal defects, such as DiGeorge Syndrome.

This is a three-year studentship, funded by the Anatomical Society of Great Britain and Ireland, and supervised by Prof Anthony Graham, at the MRC Centre for Developmental Neurobiology at Kings College London is available from Oct 2010. Studentships are normally available to British, Irish or European citizens who have spent at least three years at a British, Irish or European university and have obtained a degree with first class or upper second class honours or an equivalent qualification.

The stipends is £15,510 per annum

Reference:

Graham, A., Okabe, M. and Quinlan, R. (2005). The role of the endoderm in the development and evolution of the pharyngeal arches. Journal of Anatomy 207, 479-487

Applications  should be sent to Prof Anthony Graham - Anthony.graham@kcl.ac.uk

MRC Centre for Developmental Neurobiology

4th Floor New Hunts House

King's College London

London

SE1 1UL

Closing Date 1st April