Postdoctoral Training Fellow in Data-driven (Computational) Biology

The Francis Crick Institute

Contract:  Fixed-Term (4 years), Full- time            

The Francis Crick Institute (the Crick) is a research institute dedicated to discovering the fundamental biology underlying human health, with the aim of improving the diagnosis, treatment and prevention of human disease.


We seek a talented and motivated postdoc in Data-driven computational biology to join Markus Ralser’s laboratory, ‘Dynamics and evolution of metabolic networks’, at the Francis Crick Institute.

Dr Ralser’s laboratory focuses to understand how cellular metabolism, the network of biochemical reactions in the cell, is regulated, how it evolved, and how it maintains functional integrity in the ever changing environment the cell is exposed to. This research addresses fundamental problems in the life sciences, where knowledge about cellular metabolic systems is required to develop new therapeutics and to understand the molecular basis of disease.

Project Scope/ Description

The research aims to understand how cells respond to changes in their immediate environment. Particular focus is set to dissect the reconfigurations occurring in cellular metabolism, under circumstances when cells prevent a collapse of their metabolic system upon a sudden change in the available nutrients. For this, time-resolved quantitative data, obtained by transcriptomics, mass spectrometry and nuclear magnetic resonance spectrometry will be analysed by methods of machine learning, and mapped to biological pathways. 

Please note: all offers of employment are subject to successful security screening and continuous eligibility to work in the United Kingdom.

If you are interested in applying for this role, please apply via our website:

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