University of Edinburgh - Institute of Genetics and Molecular Medicine (IGMM)
|Salary:||£32,004 to £38,183|
|Contract Type:||Contract / Temporary|
|Placed on:||11th October 2016|
|Closes:||10th November 2016|
|★ View Employer Profile|
We are seeking an outstanding postdoctoral fellow with an interest in Transposable Elements and Genome biology to take up a post in Dr Jose L. Garcia-Perez’s lab at the Institute of Genetics and Molecular Medicine (IGMM), University of Edinburgh. The post holder will join a dynamic and multidisciplinary lab with a focus on understanding the impact that the mobility of active Transposable Elements exert on humans and model organisms. Specifically, this position aims to understand how epigenetic mechanisms act to control the mobility of LINE retrotransposons on pluripotent genomes. The Garcia-Perez lab has a long-lasting interest in understanding the biology of Transposable Elements and the group has a strong interest in epigenetics, pluripotency and genome stability (Coufal et al., Nature 460 (7259):1127-31; Garcia-Perez et al., Nature 466 (7307):769-73; Heras et al., Nature SMB 20(10):1173-81; Klawitter et al., Nature Commun 7:10286).
Candidates must have a PhD (or anticipate completing a PhD within the year) and will need to demonstrate a strong track record and previous experience in molecular and cell biology, biochemistry or genetics. Previous experience with the animal model zebrafish will be acknowledged. The successful candidate will be self-motivated, will carry out functional studies using in vitro models, cell-based models and in vivo experimental models of LINE-1 retrotransposition. To do that, the successful candidate will need to perform basic methods of biochemistry and molecular and cell biology including cell culture, transfection, purification of tagged proteins and identification of interactors, Western blot and nucleic acid isolation and manipulation. Additionally, the successful candidate will carry out further analyses using in vivo models of LINE retrotransposition using zebrafish. The post holder will be expected to take initiative and contribute to the development of the research programme.
For more information and to submit an application, please use the ‘apply’ button below.
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