Postdoctoral Research Associate (Cell and Developmental Biology)

University of Sheffield - Department of Oncology and Metabolism

Contract Type: Fixed-term for 15 months
Faculty: Faculty of Medicine, Dentistry and Health


We are seeking a highly motivated Postdoctoral Research Associate with a strong interest in cell and developmental biology to join the Cell Polarity and Cancer group headed by Dr Nasreen Akhtar ( The Akhtar lab investigates the mechanisms by which epithelial tissues shape and polarize using the mammary gland as a model system. 

We are in the Department of Oncology and Metabolism and members of the Bateson Centre (, an internationally recognised centre of excellence with groups focussing on tissue morphogenesis.

The successful candidate will analyse the role of physical forces in regulating tissue shape during branching morphogenesis with a particular focus on adhesion receptors and cytoskeletal mechanosignalling pathways. The work will involve a broad range of cell and molecular biology techniques and the candidate will have the exciting opportunity to work with cutting edge 3D organoid co-culture technology that simulate in vivo tissues.  

Applicants should have a PhD in a relevant field, proven record of scientific accomplishments, scientific ambition and excellent organizational and communication skills. Since the project involves the use of genetic mouse models, applicants possessing ASPA modular 1-3 home office training and/or a home office license (although outstanding candidates with other relevant skills will also be considered). Experience with molecular cloning, genetic manipulation of mammalian cells, immunofluorescence analysis and confocal imaging are essential for this post. Experience in lentiviral technology, primary tissue culture, live imaging and mouse transgenic breeding are desirable.

This full-time post is funded by the Wellcome Trust and is available from January 2017 for a period of 15 months in the first instance. 

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Northern England