Research Fellow

University of Nottingham - Respiratory Medicine

Location: University Park

Salary: £29,301 to £32,958 per annum, depending on skills and experience.

Applications are invited for the above post based at the Sir Peter Mansfield Magnetic Imaging Centre (SPMIC). The SPMIC is a jointly operated facility by the School of Physics and Astronomy and the School of Medicine to advance biomedical MRI. The centre has heavily invested into a number of new key MRI instrumentation funded through a recent Medical Research Council (MRC) major research instrumentation award. Of particular relevance for this employment opportunity is the current upgrade of 7 Tesla Philips (whole body) MRI scanner at SPMIC to enable the first human subject hyperpolarized (hp) noble gas MRI at this field strength. The objectives are (1) to explore dissolved phase (hp) 129Xe MRI in lungs and (2) the advancement of hp 83Kr MRI towards a phase 1 trial with healthy volunteers. Hp 83Kr MRI was pioneered in Nottingham and SPMIC is currently the only facility worldwide to develop this exciting new MRI contrast agent.

The successful candidate will be part of a team of interdisciplinary researchers in translational imaging who will develop a series of new MRI modalities. The successful candidate will be expected to undertake research and development in hyperpolarized (hp) krypton-83 and hp xenon-129 methodology, development of hp protocols for MRI with the focus on implementing this technology at the 7 Tesla Philips whole body MRI scanner at SPMIC. This includes optimization and further development of a novel spin exchange optical pumping hyperpolarizer, development of hp specific pulse sequences, and whole body MRI protocol development in preparation for a future phase 1 clinical trial. The person appointed will be expected to be willing to work in a multidisciplinary team, to be ready to acquire new skills (where needed), to plan and conduct work using approaches or methodologies and techniques appropriate to the type of research, and to publish the achievements at the various stages.

Candidates are expected to have experience in the production and application of hyperpolarized MRI contrast agents, preferably hyperpolarized noble gases. Alternatively, the candidate has extensive experience with MRI protocol development, preferably at whole body scanners.  A PhD (or near completion) in the wider field of magnetic resonance with a track record in hyperpolarization technology and nuclear magnetic resonance (NMR) spectroscopy, or NMR microscopy, or biomedical MRI with experience in pulse programming is required.

This is full-time, fixed-term post until 31 August 2017.

Informal enquiries may be addressed to Professor T Meersmann, tel: 0115 951 4752, Email: Please note that applications sent directly to this Email address will not be considered.

The University of Nottingham is an equal opportunities employer and welcomes applications from all sections of the community.

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Midlands of England