PhD Studentship: Investigating the role of MAP triple kinases as key regulators of plant innate immunity

University of East Anglia - School of Biological Sciences

Start Date:  1st October 2017

No. of positions available: 1

Supervisor: Dr Frank Menke

Project description:

Plants sense microbial pathogens through the detection of pathogen associated molecular patterns (PAMP) and this is mediated by cell surface localised pattern recognition receptors (PRR). Perception of PAMPs triggers a signaling network that includes activation of mitogen activated protein kinases (MAPK), activation of defence gene expression and ultimately leads to PAMP triggered immunity (PTI). What connects activated PRRs to downstream MAPKs has remained elusive. We have identified potential candiate phospho-proteins that could bridge the gap in our understanding of PRR signaling. In the current project the receptor based signaling event will be studied with advanced proteomics approaches, molecular genetics approaches and cell biology (using confocal microscopy). Project will also involve significant protein biochemistry allowing for a broad training of the candidate.

Further information can be found at or by contacting

Person specification:  Minimum entry 2:1

Funding notes: Full Studentships cover a stipend (RCUK rate: £14,296pa – 2016/7), research costs and tuition fees at UK/EU rate, and are available to UK and EU students who meet the UK residency requirements.

Students from EU countries who do not meet the UK residency requirements may be eligible for a fees-only award. Students in receipt of a fees-only award will be eligible for a maintenance stipend awarded by the NRPDTP Bioscience Doctoral Scholarships, which when combined will equal a full studentship. To be eligible students must meet the EU residency requirements.

Details on eligibility for funding on the BBSRC website: 

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South East England