Senior Scientific Officer (MCRC) - Clinical & Experimental Pharmacology

The University of Manchester - The Cancer Research UK Manchester Institute

  • Duration: Fixed term until March 2018 (in the first instance)

We are currently looking for two Senior Scientific Officers to join the Clinical and Experimental Pharmacology Group (CEP) of Prof Caroline Dive to help build on our successful work with cancer biomarkers. The post holders will join an expanding team who are establishing personalised medicine approaches using a range of molecular biology techniques applied to patient samples with an emphasis on blood samples. In addition to playing a major role in the technical development of novel biomarker assays the post holders will also be responsible for ensuring the assays are compliant with Good Clinical Practice (GCP) to ensure the data can be used to improve cancer patient treatment. One primary research project will be to develop and establish biomarker assays to examine a panel of genes in circulating tumour DNA (ctDNA) present in the blood of patients to be treated in the Phase I Trials Unit at the Christie Hospital (The TARGET protocol), with the aim of helping improve the clinical management of these patients.

The successful applicants should have a minimum of a BSc in biological sciences (or equivalent), plus relevant experience of working in a laboratory environment. Highly desirable is a keen interest in cancer biology and previous experience of molecular biology techniques, ideally working in a cancer research setting.

For any informal enquiries about this post, please contact Dr Ged Brady via email

The Cancer Research UK Manchester Institute (, an Institute of The University of Manchester (, is a world-leading centre for excellence in cancer research. The Institute is core funded by Cancer Research UK (, the largest independent cancer research organisation in the world. We are adjacent to The Christie NHS Foundation Trust (, one of the largest cancer treatment centres in Europe. These factors combine to provide an exceptional environment in which to pursue basic, translational and clinical research programmes.

Our aim is to understand the fundamental basis of cancer and apply that knowledge to developing new treatment strategies for cancer patients. Our advanced research programmes span a spectrum of cancer research, from the molecular and cellular basis of cancer through to drug discovery, translational research and clinical trials.

The Institute has outstanding laboratory facilities and exceptional core services, including next generation sequencing, microarrays, confocal microscopy, bioinformatics, histology and mass-spectrometry.

We are situated in Manchester, England, a vibrant and dynamic city that is surrounded by beautiful countryside and has excellent transport links both nationally and internationally.

To apply for this position please visit our website:

For applicants who are unable to download this information from our website, please contact HR department on 0161 446 3231, email: to have this information sent by post.

The deadline for receipt of applications is: 5 December 2016.

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