Research Associate

University of Cambridge - Department of Haematology

Applications are invited for a highly motivated Research Associate to join Dr. Ana Cvejic's research group at the University of Cambridge, Department of Haematology (http://www.haem.cam.ac.uk/staff/senior-staff/dr-ana-cvejic/).

Blood stem cells need to both perpetuate (self-renew) themselves and differentiate into all mature blood cells, to maintain blood formation throughout life. However, it is unclear how the underlying gene regulatory network maintains this population of self-renewing and differentiating stem cells, and how it accommodates the transition from a stem cell to a mature blood cell. Clarifying how HSCs differentiate into diverse cell types is important for understanding how this process is subverted in the generation of blood pathologies.

Dr. Ana Cvejic's group aims to bridge this knowledge gap by providing a method in a relevant model organism (zebrafish, Danio rerio) to dissect the role of novel blood genes and to determine their hierarchical position in regulatory networks that underlie haematopoiesis. The work will involve a number of molecular biology techniques in particular single cell transcriptomics and cell biology techniques. The roleholder will be involved in development of inflammation/infection models in zebrafish and will study how the inflammatory signals influence the pace and direction of HSC differentiation.

The role holder will have significant experience in molecular and cell biology. The role holder will be able to demonstrate independent, critical thinking, will be hard working, passionate about science, and keen to learn and improve skills in an outstanding research environment. Knowledge or interest in the field of haematology and inflammation would be highly advantageous.

The successful candidate must hold a PhD in a relevant related subject.

This position is full time and is funded by European Research Council (ERC).

Fixed-term: The funds for this post are available for 36 months in the first instance.

Once an offer of employment has been accepted, the successful candidate will be required to undergo a health assessment and a security check.

To apply online for this vacancy and to view further information about the role, please visit: http://www.jobs.cam.ac.uk/job/11515. This will take you to the role on the University’s Job Opportunities pages. There you will need to click on the 'Apply online' button and register an account with the University's Web Recruitment System (if you have not already) and log in before completing the online application form.

Interviews are likely to be held in the week commencing 16 January 2017.

Bhavni Sharma is responsible for the recruitment for this post and can be contacted at haemhr@hermes.cam.ac.uk.

For informal enquiries please contact Dr. Ana Cvejic, email: as889@cam.ac.uk

Please include details of your referees, including email address and phone number, one of which must be your most recent line manager.

Please quote reference RB10169 on your application and in any correspondence about this vacancy.

The University values diversity and is committed to equality of opportunity.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

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South East England