Postdoctoral Researcher - Computational Biology and Stratified Medicine

Queen Mary University of London - William Harvey Research Institute

Postdoctoral Researcher - Computational Biology and Stratified Medicine

We are seeking to appoint a Postdoctoral Researcher Bioinformatician in Computational Biology and Stratified Medicine to promote the delivery of high-quality computational biology research. The successful candidate will join an integrated, multidisciplinary research team of Scientists, Clinicians, Biostatisticians and Computational Biologists, led by Professor Costantino Pitzalis, focused on Inflammation and Rheumatology research at the William Harvey Research Institute (WHRI) and partner institutions on our picturesque Charterhouse Square campus.

The Centre also extends to the Barts Arthritis Centre at Mile End Hospital, Barts Heath NHS Trust as an integral part of its strategy to deliver best research for best care. EMR research aims to better understand disease pathogenesis in order to develop novel therapeutics and maximise therapeutic utility of existing therapies for a number of autoimmune conditions including RA, SLE and Sjogren’s Syndrome.

The post will be jointly affiliated with the Centre for Translational Bioinformatics (CTB), led by the WHRI Director of Bioinformatics, Dr Michael Barnes. The CTB is multi-disciplinary team of Computational Biologists, Software Engineers and Data Scientists, leading bioinformatics across diverse research consortia. The team are pioneering the application of multi-omics in stratified healthcare, using cutting edge computational systems biology and data warehousing in a virtualised computing environment. As a member of this dynamic growing team, you will have the opportunity to learn new computational techniques and will have access to state of the art computing facilities, including MRC-eMedlab (

As a core member of both the EMR and the CTB matrix team, you will lead bioinformatics support for the EMR, working closely with clinicians and laboratory scientists to bring novel computational insight to the EMR research portfolio. You will be particularly focused on using computational biology techniques to gain an integrated view of RA disease pathology and therapeutic response. You will lead RNA-seq and transcriptomic analysis to identify genes and pathways linked to biologic response in Rheumatoid Arthritis.

Working with a range of Omic data, you will formulate new integrative systems biology models leading to the development of new stratified medicine opportunities. This post is an excellent opportunity for an experienced postdoctoral computational biologist, seeking growing independence in their research career, who can show truly strategic leadership within the EMR, bringing insight from the diverse research portfolio of the Centre for Translational Bioinformatics.

The post is full time and on a 3 year fixed term contract.

The starting salary will be £44,327 - £49,486 per annum inclusive of London Allowance. Benefits include 30 days annual leave, defined benefit pension scheme and interest-free season ticket loan.

Candidates must be able to demonstrate their eligibility to work in the UK in accordance with the Immigration, Asylum and Nationality Act 2006. Where required this may include entry clearance or continued leave to remain under the Points Based Immigration Scheme.

Informal enquiries about this post are welcome and can be made to Dr Michael Barnes ( or +44 0207882059 or Professor Costantino Pitzalis ( or +44 7882 8192.

Details about the William Harvey Research Institute can be found on

To apply please click on the “Apply Online” for this job link below

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