Research Associate

University of Sheffield - Faculty of Science, Department of Molecular Biology & Biotechnology

Location: Firth Court, Main Campus

Applications are invited for a postdoctoral scientist to work in the group of Prof. Stuart Wilson in the Department of Molecular Biology and Biotechnology at the University of Sheffield. The department was ranked 1st in biomedical sciences and =5th in biological sciences in the U.K. in the last national census (REF2014). The BBSRC funded post will explore how RNAs, including mRNAs and long non-coding RNAs are localised in human cells in the nucleus and cytoplasm. You will also investigate how RNA localisation is altered in response to cellular stresses such as DNA damage. The project will exploit state-of-the-art technologies including CRISPR/CAS9 genome-editing and Next Generation RNA sequencing as well as other molecular, cellular and biochemical techniques. The successful applicant will join a well funded laboratory which forms a part of the Sheffield Institute For Nucleic Acids (SInFoNiA) (http://genome.sheffield.ac.uk). SInFoNiA provides an exciting and collaborative work environment involving 19 different laboratories working on many aspects of nucleic acid biology. SInFoNiA has state of the art research facilities at its disposal (http://genome.group.shef.ac.uk/facilities/) including mass spectrometry, next generation DNA sequencing, bioinformatics support and provides a world class research environment.

Candidate requirements:

You will have a recent PhD in an area of molecular biology, biochemistry or genetics, with an outstanding academic track record and at least one first-authored research publication in an internationally recognized peer-reviewed journal. You will have a strong background in biochemistry, molecular biology, cellular biology and a strong background in eukaryotic RNA biology or gene expression would be desirable. You will be capable of working in a team, but able to plan and work independently and will also have excellent communication skills and knowledge of the English language.

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Northern England