Post-Doctoral Scientist - Alzheimer’s disease drug discovery in human stem cell systems

Talisman Therapeutics Ltd

Talisman Therapeutics Ltd is a cutting-edge, stem-cell, drug discovery company based in Cambridge, UK. Building upon the world class knowledge and skills of its team, Talisman is committed to revolutionising the treatment of Alzheimer’s disease by identifying novel drug therapies.

We are currently seeking to recruit a hard-working, enthusiastic, PhD-level scientist to join our expanding team. The role will support the delivery and management of a number of different research projects and provides an opportunity to combine working in cutting-edge technologies with opportunities for team leadership. Tasks include using human stem cell models of Alzheimer’s disease for drug discovery and pathway validation.

Techniques include cell culture (including human stem cell culture), general molecular biology, and confocal microscopy. Candidates must be able to work independently, be collaborative and collegiate, and to demonstrate proven research and team management capabilities.

Key areas of responsibility:

  • Design and management of research projects;
  • Generation of human neurons and neural networks from iPS cells;
  • Conduct experimental work and subsequent analysis required for drug discovery and pathway validation in human stem cell systems;
  • Report writing and presentation of findings.

Essential skills and qualifications:

Essential qualifications are a minimum of a 2.1 class honours degree in the biological sciences and a PhD in the biological or physical sciences.

Essential skills include advanced hands-on skills in one of: molecular biology, cell culture, neuroscience or neurodegeneration research. It is also desirable for the successful candidate to have advanced knowledge of molecular biology and/or biochemistry and/or other relevant cell biology experience.

We require a minimum of two years post-qualification experience in academic and/or commercial settings.

The role will be based at the Babraham Research Campus, Cambridge. We can offer the successful candidate excellent benefits and remuneration. Salary will be in the region of £28,000-£38,000 depending on experience. Should you wish to be considered for this position, please send a CV and covering letter to by Friday, 9th December at 12:00 noon.

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South East England