Postdoctoral Research Fellow

University of Sussex - School of Life Sciences

Fixed term until 31 January 2019

Starting salary starting at £32,004 and rising to £ 38,183 per annum

Expected start date within 1 month of 1 Jan 2017

The School of Life Sciences is at the forefront of research in the biological sciences in the UK, coming in the top 10 in the REF 2014.

Project title: Investigating the effect of MTC on tau assembly

Applications are invited for a full-time Post-doctoral Research Fellow to join the multidisciplinary research team of Professor Louise Serpell in the School of Life Sciences at the University of Sussex.

Tau is known to play a central role in Alzheimer’s disease where it’s deposited in neurofibrillary tangles. Tau has become a recent target for therapeutics. The team are working with TauRX/Wista to investigate the mechanism of action of a methylene blue derivative on tau assembly and disassembly. The project will involve structural biology and biophysical approaches to investigate the effects of the compound on the structure and assembly of the tau protein.

We are seeking a post-doctoral research fellow to work on this ongoing project.

The post will be centred within the Biochemistry and Biomedicine subject group and Sussex Neuroscience within the School of Life Sciences. The research project will involve electron microscopy, X-ray fibre diffraction, NMR, spectroscopic techniques. Previous expertise in working with self-assembling or amyloidogenic proteins/peptides and biophysical approaches is essential.

The School is committed to equality and valuing diversity, and currently holds an Athena SWAN Silver Award. Applications are particularly welcomed from women and black and minority ethnic candidates, who are under-represented in academic posts in science and engineering at Sussex.

The University offers various schemes to provide real benefits to parents, these can be found at http://www.sussex.ac.uk/humanresources/personnel/familyfriendlypolicies

Potential candidates are strongly encouraged to make informal contact with Prof. Louise Serpell before applying.

Applications should be accompanied by a full CV, a statement of research interests and aspirations (not more than 4 pages), and the names of three academic referees.

The University of Sussex is committed to equality of opportunity

For full details and how to apply see www.sussex.ac.uk/jobs

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