Principal Scientific Associate

University of Cambridge - Cancer Research UK Cambridge Institute

In 2013, Europe's top cancer charity, Cancer Research UK, combined with the University of Cambridge to fund the world class Cancer Research UK Cambridge Institute, situated on the Addenbrooke's Biomedical Campus in Cambridge.

As part of the University Of Cambridge School Of Clinical Medicine, the Institute's research ranges from basic cancer biology through translational cancer research to clinical application. The Institute currently houses over 350 researchers and support staff with 22 research groups. It provides a highly collaborative, multi-disciplinary environment in cancer research, with state of the art facilities and core scientific resources, and good links with the scientific community of Cambridge.

We are currently recruiting for a new research group that will focus its research on metabolic imaging by hyperpolarized magnetic resonance, with an emphasis on new technological developments. Hyperpolarized Magnetic Resonance (MR) is a revolutionary and promising technique with a proven potential in biomedicine. Based on Dynamic Nuclear Polarization (DNP), a low-temperature technique used to increase the nuclear spin order, hyperpolarization leads to an improvement in signal-to-noise ratio on the order of 10,000 times. It allows for the detection of tiny amounts of biological substances in vivo and to follow the metabolic pathways of chosen molecules.

A Principal Scientific Associate position is now available for a highly talented and motivated individual interested in providing project management, scientific support and training to other team members, including Research Associates, and PhD students. The post involves administration and management of lab finances and operations, interactions with the core facilities. The successful candidate will be expected to use their initiative and creativity to solve routine and non-routine problems related to research projects and technical development projects.

The selected candidate will be involved in the development of new technologies and protocols to perform in vitro and in vivo DNP-enhanced MR experiments. We are seeking candidates with a PhD in Physics plus previous research associate experience in biomedical instrumentation development, in particular instruments involving a cryogenic environment. The candidate is expected to have a strong background in MR physics from their PhD, as well as good knowledge in chemistry. Experience in hyperpolarized MR and its biomedical applications would be highly desirable. A good knowledge of the Secondary ion mass spectrometry (SIMS) techniques would be an advantage.

Potential candidates must display an ability to undertake project management, work within a multi-disciplinary team environment, have excellent presentation and communication skills and the ability to train and coach other team members. The successful candidate will be able to assess, interpret and evaluate outcomes of research and translate knowledge of advances in the subject areas into research activity. They will work closely with the group leader as the lab manager and facilitate the establishment of the lab, implement technologies, perform daily management tasks, teach techniques to new lab members and assist with development and optimisation of research projects independently.

Fixed-term: The funds for this post are available for 60 months in the first instance.

Once an offer of employment has been accepted, the successful candidate will be required to undergo a basic disclosure (criminal records check) check and a security check.

To apply online for this vacancy and to view further information about the role, please visit: This will take you to the role on the University’s Job Opportunities pages. There you will need to click on the 'Apply online' button and register an account with the University's Web Recruitment System (if you have not already) and log in before completing the online application form.

Please ensure that you upload a covering letter and CV in the Upload section of the online application. If you upload any additional documents which have not been requested, we will not be able to consider these as part of your application.

The closing date for applications is Sunday 23rd October 2016.

Please include details of your referees, including email address and phone number, one of which must be your most recent line manager.

Please quote reference SW10216 on your application and in any correspondence about this vacancy.

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