Research Associate - T-Cell Immunology

Imperial College London - Department of Medicine

Section of Immunology

Division of Infectious Diseases

Full time, fixed term for 12 months

Chelsea and Westminster Campus

The International AIDS Vaccine Initiative (IAVI) Human Immunology Laboratory (HIL), located at the Chelsea and Westminster Hospital invite applications from highly motivated and experienced individuals to the post of Research Associate. You will contribute to the effort towards the development of a safe and effective HIV vaccine by joining a wider consortium called ADVANCE (Accelerate the Development of Vaccines and New Technologies to Combat the AIDS Epidemic). This 5-year USAID-funded initiative aims to dramatically accelerate development of a safe and effective HIV vaccine, and may ultimately serve as a model for developing vaccines against other emerging diseases.

You must have a PhD (or equivalent) in immunology or a related subject with a focus on T-cell biology. The candidate is also expected to have experience of developing novel cell based biological assays to interpret immune phenotype and function with a quantifiable readout. This will be based upon both in vitro and ex vivo analysis of human samples which are HIV infected and/or of human vaccine trial origin.

The project will characterize the mechanism of action and kinetics of CD8 killing of HIV infected CD4+ cells using phenotypic flow cytometry and assessment of molecular signature with cell sorted transcriptomics and soluble factor assessment within an in vitro Viral Inhibition Assay (VIA)

The individual will be expected to act as a technical expert for the Department and interact closely with a multi-disciplinary teams in the UK, US and Africa.

You must have excellent verbal and written communication skills. You must also be able to relate well with others, form positive relationships with a wide range of people and to work as part of a team, as well as independently. A creative approach to problem solving, the ability to develop and apply new concepts, techniques and methods are essential. You must also be highly motivated, committed to meeting deadlines, and have the ability to show initiative. The ideal candidate will have the passion and drive to tackle and overcome scientific problems.

For further information about the post, please contact Ed McGowan (e.mcgowan@imperial.ac.uk).

To apply for this vacancy, please click Apply Online below (please select “Job Search” then enter the job title or vacancy reference number into “Keywords”). Please complete and upload an application form as directed quoting reference number HM2016215.

Alternatively, if you are unable to apply online, please email n.hannan@imperial.ac.uk to request an application form.

Closing Date: 8 January 2016 (Midnight GMT)

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