Research Technician

University of Birmingham - College of Medical and Dental Sciences

Institute of Cancer and Genomic Sciences

Full Time, Fixed term until 31 March 2022

The postholder will be employed on the MOL-RSRC project, a 5 year grant funded by Cancer Research UK and led by Dr Andrew Beggs, to examine the molecular determinants of chemoradiosensitivity in rectal cancer. The grant involves the development of model organoid cultures of radiosensitive and radioresistant organoids that will then be subjected to genomic analysis, a targeted drug screen and in vitro CRISPR/RNAi modification. The postholder will also work as part of the larger CRUK funded Human Cancer Models Initiative (HCMI), a collaborative project involving the Wellcome Trust Sanger Institute and Universities of Birmingham, Cambridge and Southampton.

The candidate will have experience in cell culture and interventions (such as transfection) and molecular genetics. Ideally, the candidate will have experience of next generation sequencing techniques such as library preparation and sequencing, although training can be provided to suitable candidates with appropriate experience of molecular genetics for this aspect of the post if necessary. The postholder will also be expected to undertake general laboratory duties and administration, as required.

For further information about the post please contact Dr Andrew Beggs (

Full time starting salary is normally in the range £21,904 to £23,532.

To download the details of this position and submit an electronic application online please click on the Apply Online button below, please quote the appropriate Job Ref in all enquiries, alternatively information can be obtained from

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Midlands of England