Postdoctoral Research Fellow

University of Edinburgh - Queen's Medical Research Institute

A new team member is needed to drive forward our successful programme in post-inflammatory systemic senescence! This post-doctoral research post is funded through a UK Medical Research Council Senior Clinical Fellowship to Damian Mole (http://www.insight.mrc.ac.uk/2017/03/30/working-life-surgeon-researcher-damian-mole/) and is based in the MRC Centre for Inflammation Research at the University of Edinburgh. Damian’s lab is driving forward the understanding of why people who develop multiple organ failure after systemic inflammation, for example that caused by acute pancreatitis, have worse outcomes despite making an apparently complete recovery in the early phase. The project will use experimental models of systemic inflammation (mostly acute pancreatitis) in unique genetically-altered mice, coupled with a full supporting repertoire of in vitro and molecular assays, building on our recent paper in Nature Medicine. The scientific focus is on the kynurenine pathway of tryptophan metabolism, DNA and telomere damage, leading to cellular senescence. Damian’s lab works closely with clinical teams, and there will be an opportunity to engage with the translational aspects of the project, and also with industry (see http://www.dpac.gsk.com/case-studies-uedinburgh.html). Enthusiasm, commitment, and teamwork are valued as much as technical expertise. The team is well-supported – whoever joins will be part of a team of Damian, Xiao (experienced post-doc), Julia (clinical project manager), Silje (Comms Strategist), and Lucile (PhD student); interacting with collaborators within Edinburgh and internationally. Post available from 1st September 2017 but could hold for the correct candidate if notice period is required. Please get in touch with Damian directly (damian.mole@ed.ac.uk) if you would like to chat informally to see if we are right for you, although Damian will only be able to respond after 25th July 2017.

This post is available on a fixed-term basis, with a working pattern of 35 hours per week, until 31st January 2022.

Ref: 040478

Closing Date: 14th August 2017.

For more information and to submit an application, please use the ‘apply’ button below.

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