Postdoctoral Research Fellow - Molecular Mechanisms of DNA Repair in Mycobacteria

University of Sussex - School of Life Sciences

Applicants are invited to apply for a BBSRC-funded postdoctoral position to study DNA repair mechanisms in prokaryotic cells. Bacteria, in common with eukaryotes, possess a myriad of DNA repair pathways required to maintain genome stability.

The aim of this project is to study the molecular mechanism of a novel damage repair complex recently discovered in mycobacteria. Specifically, we would like to identify the components of this repair complex and define its molecular mechanism by reconstituting this repair process in vitro.

Applicants must have extensive experience in using biochemical, biophysical and molecular biology techniques to study the molecular interactions and mechanisms of protein complexes involved in DNA / RNA repair, replication, transcription or related cellular processes.

The successful applicant will join the Genome Damage and Stability Centre, an internationally renowned Institute carrying out research on the response of cells to DNA damage, genome instability and its relationship to disease.

We provide a stimulating and supportive research environment and our expertise covers a wide range of experimental systems. Further information about our research can be obtained from our website at http://www.sussex.ac.uk/gdsc/.

Informal enquiries to: Prof. Aidan Doherty

E-mail: AJD21@sussex.ac.uk; Tel: +44 1273 877500.

Potential candidates are strongly encouraged to make informal contact with Prof. Aidan Doherty before applying. E-mail: AJD21@sussex.ac.uk; Tel: +44 1273 877500.

For full details and how to apply see our vacancies page

The University of Sussex is committed to equality of opportunity

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South East England