Postdoctoral Research Associate in Molecular Parasitology

University of Oxford - Department of Biochemistry

South Parks Road, Oxford

We are seeking to appoint a Postdoctoral Research Associate, to be part of a group of 8 - 10 people who use structural and biophysical methods to understand parasite surface proteins and their interactions with human receptors and inhibitory antibodies. We have significant experience in working with these complex surface proteins, with the capacity to express and purify them from bacterial, insect cell and mammalian cell systems. Of particular interest are the surface proteins of the Plasmodium parasites, the causative agents of malaria. In recent years we have determined the structures of a number of these essential surface proteins in complex with inhibitory antibodies. We now aim to use molecular modelling approaches to design vaccine immunogens that specifically present key epitopes to the immune system.

Applicants should possess a doctorate (awarded or due to be awarded soon) in biochemistry, molecular biology or structural biology, and should have successfully used Rosetta-based tools for protein design. You should have a pro-active determination to drive forwards an important research project, as well as an enthusiasm for vaccine design and for learning new methods and applying them to solve important biological problems. You should also have the ability to work collaboratively with other laboratory members, whilst pushing forward an independent project.

This full-time fixed-term post is funded by the Wellcome Trust for up to 12 months.

Further particulars, including details of how to apply, can be obtained from the document below.

The closing date for applications is 12.00 noon on Wednesday 30 August 2017, with interviews for shortlisted candidates to be held as soon as possible thereafter.

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