Scientific Officer 1 - Clinical and Experimental Pharmacology Group

The University of Manchester - The Cancer Research UK Manchester Institute

Duration: Fixed term until 31st October 2018

We are currently looking for a Scientific Officer within Professor Caroline Dive’s Clinical and Experimental Pharmacology Group. The aim of this post is to support the day to day running of the preclinical team and carry out research under supervision as directed by the Group Leader and Preclinical Pharmacology Team Leader. The successful applicant will additionally support the Manchester-Cambridge collaborative COLorectal ORganoid project aimed at establishing patient-derived primary cell colorectal cancer models from circulating tumour cells to support a personalised medicine program.  The ultimate aim is to assess response to novel therapies using these models and thereby assist individual patient’s treatment selection in a clinically-actionable time frame.

The successful applicant should have relevant experience of working within a laboratory setting, particularly using mammalian cell culture. They should also be familiar with basic laboratory skills such as western blotting, real time PCR and microscopy. Highly desirable is a BSc in Biological Sciences (or related subject) or equivalent relevant experience working in a cancer research setting, coupled with knowledge of colorectal cancer, primary cell culture, and circulating tumour cells.

For any informal enquiries about this post, please contact Kris Frese, email:

The Cancer Research UK Manchester Institute (, an Institute of The University of Manchester (, is a world-leading centre for excellence in cancer research. The Institute is core funded by Cancer Research UK (, the largest independent cancer research organisation in the world. We are currently situated at the internationally-renowned life sciences campus at Alderley Park in Cheshire England, 15 miles from Manchester, a vibrant and dynamic city surrounded by beautiful countryside.

We are partnered with The Christie NHS Foundation Trust (adjacent to the CRUK MI Paterson Building) in South Manchester (, one of the largest cancer treatment centres in Europe. These factors combine to provide an exceptional environment in which to pursue basic, translational and clinical research programmes.

Our aim is to understand the fundamental basis of cancer and apply that knowledge to developing new treatment strategies for cancer patients.  Our advanced research programmes span a spectrum of cancer research, from the molecular and cellular basis of cancer through to drug discovery, translational research and clinical trials.

The Institute has outstanding laboratory facilities and exceptional core services, including next generation sequencing, microarrays, confocal microscopy, bioinformatics, histology and mass-spectrometry.

To apply for this position please visit our website:

Closing date: 30 August 2017.

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