Research Associate in preclinical MRI physics

University of Glasgow - RI Neuroscience and Psychology

Job Purpose

To make a leading contribution to the project:

The identification of myocardial infarction (MI) patients who can benefit from revascularisation remains one of the most challenging aspects of cardiology [1]. Ideally, an assessment of viability following myocardial ischaemia requires knowledge of both myocardial blood flow (MBF) and aerobic metabolism (myocardial oxygen consumption MVO2). Unfortunately, the current gold standard for imaging aerobic metabolism, 15O2 positron emission tomography (PET), is not practical for routine clinical use [2]. This project takes the first steps in developing a safe alternative approach based on Magnetic Resonance Imaging (MRI), using intravenous delivery of oxygen carriers pre-saturated with 17O2 gas and 17O decoupled 1H MRI. The method will be validated in vivo using a pre-clinical model of myocardial infarction. An MRI based method for imaging aerobic metabolism, combined with MRI assessment of perfusion, would allow better assessment of myocardial viability directly via "flow-metabolism mismatch".

Specifically, the postholder will conduct, manage and publish research in the area of preclinical MRI physics and in-vivo experiments as well as assist in managing and directing this complex and challenging project.

Standard Terms & Conditions

Salary will be on the University’s Research and Teaching Grade, level 7, £33,943 - £38,183 per annum.

The funding for this post is for 2 years in the first instance.

New entrants to the University will be required to serve a probationary period of 6 months.

The successful applicant will be eligible to join the Universities' Superannuation Scheme. Further information regarding the scheme is available from the Superannuation Officer, who is also prepared to advise on questions relating to the transfer of Superannuation benefits.

All research and related activities, including grants, donations, clinical trials, contract research, consultancy and commercialisation are required to be managed through the University’s relevant processes (e.g. contractual and financial), in accordance with the University Court’s policies.

It is the University of Glasgow’s mission to foster an inclusive climate, which ensures equality in our working, learning, research and teaching environment.

We strongly endorse the principles of Athena SWAN, including a supportive and flexible working environment, with commitment from all levels of the organisation in promoting gender equity.

The University of Glasgow, charity number SC004401.

Vacancy ref: M00750, closing date: 3 September 2017.

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Scotland