Senior Scientist in Bioinformatics

Imperial College London - Medicine, Brain Sciences

Campus: Hammersmith

The Division of Brain Sciences within the Department of Medicine at Imperial College London is recruiting a Senior Scientist in Bioinformatics to support the work of the NIHR Imperial Biomedical Research Centre Neuroscience Theme.

The Neurosciences Theme is developing an ambitious plan for expanding research using brain single cell ‘omics to identify novel pathways and drug targets for brain disease, with long term support as a UK Dementia Research Institute Centre, as well as from the Medical Research Council, major charities and industry. Our primary focus is on understanding dynamic molecular mechanisms of glial-neuronal interactions in neurodegenerative diseases and the epilepsies. An increasingly wide range of methods are being adopted in the Division for the integrated study of ‘omics data with isolated cells, animal models and human brain tissue; the Division of Brain Sciences at Imperial College hosts the national multiple sclerosis (MS) and Parkinson’s disease (PD) brain banks.

The post holder will provide leadership in bioinformatics for selected projects in the Neuroscience Theme. Development of an innovative, independent research programme within the Theme scientists or clinicians will be encouraged, including participation in related grant applications and the development of new funding opportunities. Opportunities for the supervision of trainees in bioinformatics and for teaching will be available.

We are seeking a highly motivated scientist. We aim to recruit a forward and outward-facing, motivated, passionate individual who will stimulate new thinking with progressive and inclusive approaches. Applications are encouraged from people who can demonstrate a strong background in quantitative transcriptomic analysis (RNA-seq, microarray) and gene regulatory analysis. Proven expertise in translating integrative genomics and gene regulatory network analysis to therapeutic discovery (drugs and drug targets) would be highly desirable. You must have considerable programming experience and experience with the statistical software R. The successful applicants will have an aptitude for visualizing data, problem solving and careful statistical analysis. You should be able to work alone as well as collaboratively, and have demonstrable evidence of effective communication of scientific ideas.

For an informal discussion of the post please contact Professor Michael Johnson (m.johnson@imperial.ac.uk) providing a copy of your CV and a statement of interest in the post.

Imperial Expectations guide the behaviour of all our staff.

Should you have any queries please contact:

Michelle Buckman – michelle.buckman12@imperial.ac.uk

Committed to equality and valuing diversity, we are also an Athena SWAN Silver Award winner, a Stonewall Diversity Champion, a Disability Confident Employer and are working in partnership with GIRES to promote respect for trans people.

The College is a proud signatory to the San-Francisco Declaration on Research Assessment (DORA), which means that in hiring and promotion decisions, we evaluate applicants on the quality of their work, not the journal impact factor where it is published. For more information, see www.imperial.ac.uk/research-and-innovation/about-imperial-research/research-evaluation

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