Postdoctoral Scientist – Cell Division

The University of Manchester

  • Fixed term for 3 years

We are looking for a highly motivated Postdoctoral Scientist to join the laboratory of Professor Iain Hagan to study the control of cell division by the Wee1 family kinase Myt1. The Wee1 inhibitor, AZD1775, is having striking impact upon some, but not all, pre-clinical models. The fact that AZD1775 is 100 times more potent as a Wee1 than Myt1 kinase inhibitor raises the possibility that the AZD1775 refractory cancers maybe protected by Myt1 kinase. This role is an exciting opportunity to develop and drive the project to characterise the basic biology of Myt1 kinase.

The successful applicant should have a PhD in Cell Biology or Biochemistry and a background in human tissue culture.

Informal enquiries should be directed to Iain Hagan at Iain.Hagan@manchester.ac.uk

The Cancer Research UK Manchester Institute (www.cruk.manchester.ac.uk), an Institute of The University of Manchester (www.manchester.ac.uk), is a world-leading centre for excellence in cancer research. The Institute is core funded by Cancer Research UK (www.cancerresearchuk.org), the largest independent cancer research organisation in the world. We are currently situated at the internationally-renowned life sciences campus at Alderley Park in Cheshire England, 15 miles from Manchester, a vibrant and dynamic city surrounded by beautiful countryside.

We are partnered with The Christie NHS Foundation Trust (adjacent to the CRUK MI Paterson Building) in South Manchester (www.christie.nhs.uk), one of the largest cancer treatment centres in Europe. These factors combine to provide an exceptional environment in which to pursue basic, translational and clinical research programmes.

Our aim is to understand the fundamental basis of cancer and apply that knowledge to developing new treatment strategies for cancer patients. Our advanced research programmes span a spectrum of cancer research, from the molecular and cellular basis of cancer through to drug discovery, translational research and clinical trials.

The Institute has access to outstanding laboratory facilities and exceptional core services, including next generation sequencing, microarrays, confocal microscopy, bioinformatics, histology and mass-spectrometry.

To apply for this position please visit our website: www.cruk.manchester.ac.uk.

Closing date: 11 October 2017.

Skype Interviews will take place between 30 October and 1 November 2017.

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