Research Associate

Imperial College London - Vascular Science National Heart and Lung Institute

Applications are invited for the position of Research Associate, to work in the Angiogenesis Research Group led by Dr Graeme Birdsey, to study the role of growth factor signalling in mediating the transcriptional regulation of angiogenesis.

You will work on a BHF-funded project aimed at investigating the cellular and molecular pathways controlled by isoforms of the transcription factor ERG, a master regulator of endothelial homeostasis and angiogenesis. Using in vitro and in vivo models, we have recently discovered a new role for ERG in controlling physiological and pathological angiogenesis and vascular stability (Birdsey et al., Developmental Cell 2015; Shah et al., Nature Communications 2017). The aim of this project is to define the signalling networks controlled by ERG isoforms and their role in regulating sprouting angiogenesis. The project combines biochemical studies, in vitro molecular cell biology approaches with ex vivo models, and will involve endothelial cell culture and bioinformatics analysis.

We are seeking a highly-motivated scientist to join a collaborative team of research scientists interested in vascular biology. You should have a PhD in a relevant biological discipline and have experience in studying signalling pathways. A strong background in biochemistry is essential. Previous experience in angiogenesis research and knowledge of gene transcription pathways and bioinformatics analysis would be desirable. The post will require collaboration with other groups both within and outside the Vascular Sciences department.

The post is full-time fixed-term until May 5th 2019 and based at the Hammersmith Campus, located near White City, London.

Further information on the Vascular Sciences Section can be found at: www.imperial.ac.uk/nhli/research/cardiovascular/vascular-science

Informal enquiries may be sent to Dr Graeme Birdsey (g.birdsey@imperial.ac.uk)

Our preferred method of application is online via our website www.imperial.ac.uk/job-applicants (please select “Job Search” then enter the job title or vacancy reference number into “Keywords”). Please complete and upload an application form as directed.

Alternatively, if you are unable to apply online, email rb.recruitment@imperial.ac.uk to request an application form.

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