Research Associate

UCL Institute of Neurology - UK Dementia Research Institute

In December 2016, it was announced that UCL had been selected as the 'hub' of the new £250m UK Dementia Research Institute (UK DRI), to be led by Professor Bart De Strooper. The UK DRI is a joint £250m investment into dementia research led by the Medical Research Council (MRC) alongside founding charity partners Alzheimer’s Society and Alzheimer’s Research UK.

The purpose of this position will be to work as part of a collaboration between Professor Paul Whiting (who is also Chief Scientific Officer of the ARUK Drug Discovery Institute at UCL), Professor Patricia Salinas and Dr Selina Wray, utilizing induced human pluripotent stem cell (iPSC) derived neural model systems to determine the role of the Wnt signaling pathways in health and disease. This will include understanding the role of Wnt in synapse formation and maintenance, and dissecting the Wnt mediated intercellular communication between neurons and glial cell types.  The successful applicant will have the opportunity to use a variety of techniques, including but not limited to transcriptomics, molecular and cellular, imaging and functional approaches. They will also have the opportunity to utilize the breadth and depth of expertise and technologies available across the collaborating groups, the ARUK Drug Discovery Institute and the DRI.

Applicants should have a PhD in a neuroscience/neurobiology related topic and deep theoretical and practical knowledge of neurobiology. Practical experience in a breadth of molecular, cellular and imaging techniques is essential as is a strong track record in the field, as demonstrated by publications and presentations at conferences. Experience of primary neuronal cell culture systems and in the use of induced pluripotent stem cells for generation of neuronal model systems is desirable.

The post is available from January 2018, and is funded by UK DRI @ UCL for three years in the first instance.

For further information on the post please contact Professor Paul Whiting (email: p.whiting@ucl.ac.uk)

For further information regarding the application process please contact Samantha Robinson, HR Officer, UCL Institute of Neurology (email: IoN.HRAdmin@ucl.ac.uk).

Latest time for the submission of applications: 23.59

Interview date: TBC

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