Research Assistant in Iron Homeostasis

University of Oxford - Department of Physiology, Anatomy and Genetics

Applications are invited for a Research Assistant to join Dr Samira Lakhal-Littleton’s group, to work on a project to understand the effects of synthetic hepcidin peptides on urinary iron excretion. It will build on preliminary work which suggests that renal ferroportin, the hepcidin target, is involved in iron reabsorption. The project will utilise mouse models of iron overload including genetic models (hemochromatosis) and dietary iron loading. The primary outcome measure will be the quantitation of urinary iron and of haematological and histological iron indices.

The Research Assistant will take responsibility for the day-to-day management of mouse colonies, administration of peptide, collection of urine and blood, preparation of samples and tissues for iron measurements. They will maintain animal records, and prepare routine lab reagents. They will be expected to manage their own research and administrative activities, reporting to Dr Lakhal-Littleton, who will provide guidelines as required. The post requires the coordination of multiple aspects of work to meet deadlines.

You will hold an MSC or equivalent in a relevant area of research, and have experience of animal husbandry, handling and welfare. A Home Office licence is required for this post, and you will have knowledge of HO regulations and procedures.

You will be based in the Sherrington Building, Parks Road, Oxford. The position is fixed-term for up to 12 months and funded by La Jolla Pharmaceutical, and is expected to start the beginning of January 2018.

The closing date for applications is 12.00 noon on 27 October 2017.

Interviews will be held on the week commencing November 13th 2017.

Please note that the University of Oxford's retirement policy is changing. With effect from October 1 2017, all employees at Grade 8 and above will have a retirement age of 68, and all employees at Grades 6 and 7 will no longer have a set retirement age. Further details are available at: www.ox.ac.uk/about/jobs/preemploymentscreening.

https://www.recruit.ox.ac.uk/pls/hrisliverecruit/erq_jobspec_version_4.jobspec?p_id=131114

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South East England